Anders Hojgaard Hansen
Overview
Explore the profile of Anders Hojgaard Hansen including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
19
Citations
161
Followers
0
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Recent Articles
1.
Valentini A, Schultz-Knudsen K, Hansen A, Tsakoumagkou A, Jenkins L, Christensen H, et al.
J Med Chem
. 2023 May;
66(9):6105-6121.
PMID: 37129317
The free fatty acid receptor 2 (FFA2), also known as GPR43, mediates effects of short-chain fatty acids and has attracted interest as a potential target for treatment of various metabolic...
2.
Dannheim F, Walsh S, Orozco C, Hansen A, Bargh J, Jackson S, et al.
Chem Sci
. 2022 Aug;
13(30):8781-8790.
PMID: 35975158
Antibody-drug conjugates (ADCs) are valuable therapeutic entities which leverage the specificity of antibodies to selectively deliver cytotoxins to antigen-expressing targets such as cancer cells. However, current methods for their construction...
3.
Hansen A, Christensen H, Pandey S, Sergeev E, Valentini A, Dunlop J, et al.
ChemMedChem
. 2021 Jul;
16(21):3326-3341.
PMID: 34288488
Free fatty acid receptor 2 (FFA2) is a sensor for short-chain fatty acids that has been identified as an interesting potential drug target for treatment of metabolic and inflammatory diseases....
4.
van Hees M, Slott S, Hansen A, Kim H, Ji H, Astakhova K
Mol Ther
. 2021 Jun;
30(1):32-46.
PMID: 34091053
CRISPR-Cas9 is rapidly entering molecular biology and biomedicine as a promising gene-editing tool. A unique feature of CRISPR-Cas9 is a single-guide RNA directing a Cas9 nuclease toward its genomic target....
5.
Ray R, Hansen A, Taskova M, Jandl B, Hansen J, Soemardy C, et al.
Beilstein J Org Chem
. 2021 May;
17:891-907.
PMID: 33981364
Lipid nanoparticles (LNPs) constitute a facile and scalable approach for delivery of payloads to human cells. LNPs are relatively immunologically inert and can be produced in a cost effective and...
6.
Larsen J, Bang-Berthelsen C, Qvortrup K, Sancho A, Hansen A, Andersen K, et al.
Crit Rev Biotechnol
. 2020 Jun;
40(6):881-894.
PMID: 32515236
Allergen-specific immunotherapy (IT) is emerging as a viable avenue for the treatment of food allergies. Clinical trials currently investigate raw or slightly processed foods as therapeutic agents, as trials using...
7.
Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators
Rexen Ulven E, Quon T, Sergeev E, Barki N, Brvar M, Hudson B, et al.
J Med Chem
. 2020 Mar;
63(7):3577-3595.
PMID: 32141297
Free fatty acid receptor 3 (FFA3, previously GPR41) is activated by short-chain fatty acids, mediates health effects of the gut microbiota, and is a therapeutic target for metabolic and inflammatory...
8.
Loffler P, Hansen A, Ries O, Jakobsen U, Rabe A, Sorensen K, et al.
Sci Rep
. 2019 Sep;
9(1):13856.
PMID: 31554826
The ability to manipulate and fuse nano-compartmentalized volumes addresses a demand for spatiotemporal control in the field of synthetic biology, for example in the bottom-up construction of (bio)chemical nanoreactors and...
9.
Ray R, Hansen A, Slott S, Taskova M, Astakhova K, Morris K
Mol Ther Nucleic Acids
. 2019 Jul;
17:264-276.
PMID: 31279228
Hypercholesterolemia is a condition that is characterized by very high levels of cholesterol in the blood and is a major correlating factor with heart disease. Indeed, high levels of the...
10.
Hansen A, Sergeev E, Bolognini D, Sprenger R, Ekberg J, Ejsing C, et al.
J Med Chem
. 2018 Sep;
61(21):9534-9550.
PMID: 30247908
Free fatty acid receptor 2 (FFA2/GPR43) is a receptor for short-chain fatty acids reported to be involved in regulation of metabolism, appetite, fat accumulation, and inflammatory responses and is a...