Sun Hee Yim
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Explore the profile of Sun Hee Yim including associated specialties, affiliations and a list of published articles.
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37
Citations
1966
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Recent Articles
1.
Gladyshev V, Anderson B, Barlit H, Barre B, Beck S, Behrouz B, et al.
PNAS Nexus
. 2024 Dec;
3(12):pgae499.
PMID: 39660064
To gain insight into how researchers of aging perceive the process they study, we conducted a survey among experts in the field. While highlighting some common features of aging, the...
2.
Fernando R, Shindyapina A, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, et al.
Commun Biol
. 2023 Dec;
6(1):1240.
PMID: 38066057
Skeletal muscle aging is characterized by the loss of muscle mass, strength and function, mainly attributed to the atrophy of glycolytic fibers. Underlying mechanisms driving the skeletal muscle functional impairment...
3.
Poganik J, Zhang B, Baht G, Tyshkovskiy A, Deik A, Kerepesi C, et al.
Cell Metab
. 2023 Apr;
35(5):807-820.e5.
PMID: 37086720
Aging is classically conceptualized as an ever-increasing trajectory of damage accumulation and loss of function, leading to increases in morbidity and mortality. However, recent in vitro studies have raised the...
4.
Dou Q, Turanov A, Mariotti M, Hwang J, Wang H, Lee S, et al.
J Biol Chem
. 2022 Jun;
298(8):102183.
PMID: 35753352
Thioredoxin/glutathione reductase (TXNRD3) is a selenoprotein composed of thioredoxin reductase and glutaredoxin domains. This NADPH-dependent thiol oxidoreductase evolved through gene duplication within the Txnrd family, is expressed in the testes,...
5.
Kerepesi C, Meer M, Ablaeva J, Amoroso V, Lee S, Zhang B, et al.
Nat Commun
. 2022 Jan;
13(1):355.
PMID: 35039495
The naked mole-rat (NMR) is an exceptionally long-lived rodent that shows no increase of mortality with age, defining it as a demographically non-aging mammal. Here, we perform bisulfite sequencing of...
6.
Gerashchenko M, Peterfi Z, Yim S, Gladyshev V
Nucleic Acids Res
. 2020 Dec;
49(2):e9.
PMID: 33264395
There has been a surge of interest towards targeting protein synthesis to treat diseases and extend lifespan. Despite the progress, few options are available to assess translation in live animals,...
7.
Santesmasses D, Castro J, Zenin A, Shindyapina A, Gerashchenko M, Zhang B, et al.
Aging Cell
. 2020 Oct;
19(10):e13230.
PMID: 33006233
COVID-19 is an ongoing pandemic caused by the SARS-CoV-2 coronavirus that poses one of the greatest challenges to public health in recent years. SARS-CoV-2 is known to preferentially target older...
8.
Yim S, Clish C, Gladyshev V
Cell Rep
. 2019 May;
27(9):2785-2797.e3.
PMID: 31141699
Selenium (Se) is an essential trace element because of its presence in selenoproteins in the form of selenocysteine residue. Both Se deficiency, which compromises selenoprotein functions, and excess Se, which...
9.
Lee S, Mikhalchenko A, Yim S, Gladyshev V
Stem Cell Res
. 2018 Aug;
31:197-200.
PMID: 30107334
Naked mole rats (NMRs, Heterocephalus glaber) are long-lived, cancer-resistant rodents. Here, we report the development of an induced pluripotent stem cell (iPSC) line generated from immortalized NMR embryonic fibroblasts transduced...
10.
Yim S, Everley R, Schildberg F, Lee S, Orsi A, Barbati Z, et al.
Cell Rep
. 2018 May;
23(5):1387-1398.
PMID: 29719252
Selenof (15-kDa selenoprotein; Sep15) is an endoplasmic reticulum (ER)-resident thioredoxin-like oxidoreductase that occurs in a complex with UDP-glucose:glycoprotein glucosyltransferase. We found that Selenof deficiency in mice leads to elevated levels...