Subul A Beg
Overview
Explore the profile of Subul A Beg including associated specialties, affiliations and a list of published articles.
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7
Citations
984
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0
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Recent Articles
1.
White J, Wu F, Yasin S, Moskovljevic M, Varriale J, Dragoni F, et al.
J Clin Invest
. 2023 Jan;
133(6).
PMID: 36602866
BackgroundAntiretroviral therapy (ART) halts HIV-1 replication, decreasing viremia to below the detection limit of clinical assays. However, some individuals experience persistent nonsuppressible viremia (NSV) originating from CD4+ T cell clones...
2.
Simonetti F, Zhang H, Soroosh G, Duan J, Rhodehouse K, Hill A, et al.
J Clin Invest
. 2020 Dec;
131(3).
PMID: 33301425
Clonal expansion of infected CD4+ T cells is a major mechanism of HIV-1 persistence and a barrier to achieving a cure. Potential causes are homeostatic proliferation, effects of HIV-1 integration,...
3.
Liu R, Yeh Y, Varabyou A, Collora J, Sherrill-Mix S, Talbot Jr C, et al.
Sci Transl Med
. 2020 May;
12(543).
PMID: 32404504
Understanding HIV-1-host interactions can identify the cellular environment supporting HIV-1 reactivation and mechanisms of clonal expansion. We developed HIV-1 SortSeq to isolate rare HIV-1-infected cells from virally suppressed, HIV-1-infected individuals...
4.
Bruner K, Wang Z, Simonetti F, Bender A, Kwon K, Sengupta S, et al.
Nature
. 2019 Feb;
566(7742):120-125.
PMID: 30700913
A stable latent reservoir for HIV-1 in resting CD4 T cells is the principal barrier to a cure. Curative strategies that target the reservoir are being tested and require accurate,...
5.
Bertagnolli L, White J, Simonetti F, Beg S, Lai J, Tomescu C, et al.
Nature
. 2018 Sep;
561(7723):E17-E19.
PMID: 30232425
No abstract available.
6.
Wang Z, Gurule E, Brennan T, Gerold J, Kwon K, Hosmane N, et al.
Proc Natl Acad Sci U S A
. 2018 Feb;
115(11):E2575-E2584.
PMID: 29483265
The latent reservoir for HIV-1 in resting CD4 T cells is a major barrier to cure. Several lines of evidence suggest that the latent reservoir is maintained through cellular proliferation....
7.
Pollack R, Jones R, Pertea M, Bruner K, Martin A, Thomas A, et al.
Cell Host Microbe
. 2017 Apr;
21(4):494-506.e4.
PMID: 28407485
Despite antiretroviral therapy, HIV-1 persists in memory CD4 T cells, creating a barrier to cure. The majority of HIV-1 proviruses are defective and considered clinically irrelevant. Using cells from HIV-1-infected...