Stuart Walsh
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Explore the profile of Stuart Walsh including associated specialties, affiliations and a list of published articles.
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12
Citations
2454
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Recent Articles
1.
Liu H, Zhang C, Ammanamanchi N, Suresh S, Lewarchik C, Rao K, et al.
Sci Transl Med
. 2019 Oct;
11(513).
PMID: 31597755
One million patients with congenital heart disease (CHD) live in the United States. They have a lifelong risk of developing heart failure. Current concepts do not sufficiently address mechanisms of...
2.
Mondritzki T, Boehme P, White J, Park J, Hoffmann J, Vogel J, et al.
Circ Cardiovasc Interv
. 2018 May;
11(5):e006258.
PMID: 29748220
Background: Heart failure (HF) remains the most common reason for hospital admission in patients aged >65 years. Despite modern drug therapy, mortality and readmission rates for patients hospitalized with HF...
3.
Polizzotti B, Ganapathy B, Walsh S, Choudhury S, Ammanamanchi N, Bennett D, et al.
Sci Transl Med
. 2015 Apr;
7(281):281ra45.
PMID: 25834111
Therapies developed for adult patients with heart failure have been shown to be ineffective in pediatric clinical trials, leading to the recognition that new pediatric-specific therapies for heart failure must...
4.
Ponten A, Walsh S, Malan D, Xian X, Scheele S, Tarnawski L, et al.
PLoS One
. 2014 Jan;
8(12):e82403.
PMID: 24386094
Purification of cardiomyocytes from the embryonic mouse heart, embryonic stem (ES) or induced pluripotent stem cells (iPS) is a challenging task and will require specific isolation procedures. Lately the significance...
5.
Bersell K, Choudhury S, Mollova M, Polizzotti B, Ganapathy B, Walsh S, et al.
Dis Model Mech
. 2013 Aug;
6(6):1459-69.
PMID: 23929941
Numerous mouse models have utilized Cre-loxP technology to modify gene expression. Adverse effects of Cre recombinase activity have been reported, including in the heart. However, the mechanisms associated with cardiac...
6.
Yang N, Hort J, Linforth R, Brown K, Walsh S, Fisk I
Food Chem
. 2013 Jun;
141(2):1354-60.
PMID: 23790924
The influence of choice of flavour solvent, propylene glycol (PG) or triacetin (TA), was investigated during accelerated shelf life (ASL) testing of shortcake biscuits. Specifically, the differential effect on the...
7.
Mollova M, Bersell K, Walsh S, Savla J, Das L, Park S, et al.
Proc Natl Acad Sci U S A
. 2013 Jan;
110(4):1446-51.
PMID: 23302686
The human heart is believed to grow by enlargement but not proliferation of cardiomyocytes (heart muscle cells) during postnatal development. However, recent studies have shown that cardiomyocyte proliferation is a...
8.
Walsh S, Nygren J, Ponten A, Jovinge S
PLoS One
. 2011 Dec;
6(11):e27500.
PMID: 22140444
Lack of expression of dystrophin leads to degeneration of muscle fibers and infiltration of connective and adipose tissue. Cell transplantation therapy has been proposed as a treatment for intractable muscle...
9.
Tormin A, Li O, Brune J, Walsh S, Schutz B, Ehinger M, et al.
Blood
. 2011 Mar;
117(19):5067-77.
PMID: 21415267
Nonhematopoietic bone marrow mesenchymal stem cells (BM-MSCs) are of central importance for bone marrow stroma and the hematopoietic environment. However, the exact phenotype and anatomical distribution of specified MSC populations...
10.
Fuegemann C, Samraj A, Walsh S, Fleischmann B, Jovinge S, Breitbach M
Curr Protoc Stem Cell Biol
. 2010 Dec;
Chapter 1:Unit 1F.11.
PMID: 21125557
Herein, we describe two protocols for the in vitro differentiation of mouse embryonic stem cells (mESCs) into cardiomyocytes. mESCs are pluripotent and can be differentiated into cells of all three...