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Stuart D Olver

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Articles 27
Citations 1173
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Recent Articles
1.
Takahashi S, Minnie S, Ensbey K, Schmidt C, Sekiguchi T, Legg S, et al.
Blood . 2024 Jan; 143(16):1656-1669. PMID: 38295333
Autologous stem cell transplantation (ASCT) is the standard of care consolidation therapy for eligible patients with myeloma but most patients eventually progress, an event associated with features of immune escape....
2.
Minnie S, Waltner O, Ensbey K, Olver S, Collinge A, Sester D, et al.
J Clin Invest . 2022 Dec; 133(4). PMID: 36512425
Autologous stem cell transplantation (ASCT) with subsequent lenalidomide maintenance is standard consolidation therapy for multiple myeloma, and a subset of patients achieve durable progression-free survival that is suggestive of long-term...
3.
Oyong D, Loughland J, Soon M, Chan J, Andrew D, Wines B, et al.
EBioMedicine . 2021 Dec; 75:103784. PMID: 34968760
Background: Protective malarial antibodies are acquired more rapidly in adults than children, independently of cumulative exposure, however the cellular responses mediating these differences are unknown. CD4 T-follicular helper (Tfh) cells...
4.
Yeh A, Varelias A, Reddy A, Barone S, Olver S, Chilson K, et al.
Blood . 2021 Jun; 138(26):2874-2885. PMID: 34115118
Donor and recipient cytomegalovirus (CMV) serostatus correlate with transplant-related mortality that is associated with reduced survival following allogeneic stem cell transplant (SCT). Prior epidemiologic studies have suggested that CMV seronegative...
5.
Kennedy G, Tey S, Buizen L, Varelias A, Gartlan K, Curley C, et al.
Blood . 2021 Jan; 137(14):1970-1979. PMID: 33512442
We determined the efficacy of tocilizumab (TCZ) in preventing grade 2-4 acute graft-versus-host disease (aGVHD) in patients with acute leukemia or myelodysplasia undergoing matched sibling donor (MSD) or volunteer unrelated...
6.
Varelias A, Gartlan K, Wilkinson A, Olver S, Samson L, Tey S, et al.
Blood Adv . 2019 Mar; 3(5):718-723. PMID: 30814056
No abstract available.
7.
Zhang P, Raju J, Ullah M, Au R, Varelias A, Gartlan K, et al.
Clin Cancer Res . 2019 Feb; 25(6):1749-1755. PMID: 30765390
Purpose: Inducible caspase 9 () is a cellular safety switch that can make T-cell therapy safer. The purpose of this phase I trial was to investigate the use of -transduced...
8.
Varelias A, Bunting M, Ormerod K, Koyama M, Olver S, Straube J, et al.
J Clin Invest . 2018 Apr; 128(5):1919-1936. PMID: 29629900
Mucosal-associated invariant T (MAIT) cells are a unique innate-like T cell subset that responds to a wide array of bacteria and yeast through recognition of riboflavin metabolites presented by the...
9.
Wilkinson A, Gartlan K, Kelly G, Samson L, Olver S, Avery J, et al.
J Immunol . 2018 Apr; 200(10):3547-3555. PMID: 29626088
IL-6 mediates broad physiological and pathological effects through its receptor signal transducing unit gp130. Due to the reportedly wide cellular expression of gp130, IL-6 is thought to signal ubiquitously via...
10.
Gartlan K, Varelias A, Koyama M, Robb R, Markey K, Chang K, et al.
Blood Adv . 2018 Jan; 1(6):341-351. PMID: 29296949
T-helper 17 (Th17) cells have been widely implicated as drivers of autoimmune disease. In particular, Th17 cytokine plasticity and acquisition of an interleukin-17A(IL-17A)interferon γ(IFNγ) cytokine profile is associated with increased...