Kelli P A MacDonald
Overview
Explore the profile of Kelli P A MacDonald including associated specialties, affiliations and a list of published articles.
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Articles
87
Citations
4037
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Recent Articles
1.
Adams R, MacDonald K, MacDonald K, Hill G
Blood
. 2024 Nov;
145(10):1010-1021.
PMID: 39576958
Macrophages execute core functions in maintaining tissue homeostasis, in which their extensive plasticity permits a spectrum of functions from tissue remodeling to immune defense. However, perturbations to tissue-resident macrophages during...
2.
Curren B, Ahmed T, Rashid R, Sebina I, Sikder M, Howard D, et al.
Cell Rep
. 2024 Nov;
43(11):114974.
PMID: 39535919
A poor maternal diet during pregnancy predisposes the infant to severe lower respiratory tract infections (sLRIs), which, in turn, increases childhood asthma risk; however, the underlying mechanisms remain poorly understood....
3.
Lineburg K, Leveque-El Mouttie L, Hunter C, Le Texier L, McGirr C, Teal B, et al.
Blood Adv
. 2024 Jan;
8(8):2032-2043.
PMID: 38295282
Autophagy is an intracellular survival process that has established roles in the long-term survival and function of hematopoietic stem cells (HSC). We investigated the contribution of autophagy to HSC fitness...
4.
Willis E, Kim S, Chen W, Nyuydzefe M, MacDonald K, Zanin-Zhorov A, et al.
Brain Behav Immun
. 2024 Jan;
117:181-194.
PMID: 38211634
Traumatic brain injury (TBI) results in prolonged and non-resolving activation of microglia. Forced turnover of these cells during the acute phase of TBI aids recovery, but the cell-intrinsic pathways that...
5.
Adams R, Carter-Cusack D, Llanes G, Hunter C, Vinnakota J, Ruitenberg M, et al.
Blood
. 2023 Dec;
143(10):912-929.
PMID: 38048572
Chronic graft-versus-host disease (cGVHD) remains a significant complication of allogeneic hematopoietic stem cell transplantation. Central nervous system (CNS) involvement is becoming increasingly recognized, in which brain-infiltrating donor major histocompatibility complex...
6.
Larson J, Jin S, Loschi M, Bolivar Wagers S, Thangavelu G, Zaiken M, et al.
Am J Transplant
. 2023 Mar;
23(8):1102-1115.
PMID: 36878433
Damage to the gastrointestinal tract following allogeneic hematopoietic stem cell transplantation is a significant contributor to the severity and perpetuation of graft-versus-host disease. In preclinical models and clinical trials, we...
7.
Buxbaum N, Socie G, Hill G, MacDonald K, Tkachev V, Teshima T, et al.
Blood Adv
. 2022 Nov;
7(17):4886-4902.
PMID: 36322878
Chronic graft-versus-host disease (cGvHD) remains a prominent barrier to allogeneic hematopoietic stem cell transplantion as the leading cause of nonrelapse mortality and significant morbidity. Tremendous progress has been achieved in...
8.
Cuvelier G, Schoettler M, Buxbaum N, Pinal-Fernandez I, Schmalzing M, Distler J, et al.
Transplant Cell Ther
. 2022 Jun;
28(8):426-445.
PMID: 35662591
Alloreactive and autoimmune responses after allogeneic hematopoietic cell transplantation can occur in nonclassical chronic graft-versus-host disease (chronic GVHD) tissues and organ systems or manifest in atypical ways in classical organs...
9.
Zaiken M, Flynn R, Paz K, Rhee S, Jin S, Mohamed F, et al.
Blood
. 2022 Feb;
139(19):2983-2997.
PMID: 35226736
Despite advances in the field, chronic graft-versus-host-disease (cGVHD) remains a leading cause of morbidity and mortality following allogenic hematopoietic stem cell transplant. Because treatment options remain limited, we tested efficacy...
10.
Keshvari S, Genz B, Teakle N, Caruso M, Cestari M, Patkar O, et al.
Dis Model Mech
. 2022 Feb;
15(4).
PMID: 35169835
Resident and recruited macrophages control the development and proliferation of the liver. We have previously shown in multiple species that treatment with a macrophage colony stimulating factor (CSF1)-Fc fusion protein...