Stuart A Cain
Overview
Explore the profile of Stuart A Cain including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
42
Citations
1221
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Cain S, Woods S, Singh M, Kimber S, Baldock C
Matrix Biol
. 2022 Nov;
114:18-34.
PMID: 36368447
The ADAMTS superfamily is composed of secreted metalloproteases and structurally related non-catalytic ADAMTS-like proteins. A subset of this superfamily, including ADAMTS6, ADAMTS10 and ADAMTSL2, are involved in elastic fiber assembly...
2.
Mead T, Martin D, Wang L, Cain S, Gulec C, Cahill E, et al.
Elife
. 2022 May;
11.
PMID: 35503090
The embryonic extracellular matrix (ECM) undergoes transition to mature ECM as development progresses, yet few mechanisms ensuring ECM proteostasis during this period are known. Fibrillin microfibrils are macromolecular ECM complexes...
3.
Smith C, Humphreys P, Bates N, Naven M, Cain S, Dvir-Ginzberg M, et al.
FASEB J
. 2022 Apr;
36(5):e22314.
PMID: 35416346
Epigenetic modification is a key driver of differentiation, and the deacetylase Sirtuin1 (SIRT1) is an established regulator of cell function, ageing, and articular cartilage homeostasis. Here we investigate the role...
4.
Lockhart-Cairns M, Cain S, Dajani R, Steer R, Thomson J, Alanazi Y, et al.
Matrix Biol
. 2022 Feb;
107:24-39.
PMID: 35122964
TGFβ superfamily members are potent growth factors in the extracellular matrix with essential roles in all aspects of cellular behaviour. Latent TGFβ binding proteins (LTBPs) are co-expressed with TGFβ, essential...
5.
Alanazi Y, Lockhart-Cairns M, Cain S, Jowitt T, Weiss A, Baldock C
Front Genet
. 2021 Sep;
12:706662.
PMID: 34539739
Latent TGFβ binding protein-4 (LTBP4) is a multi-domain glycoprotein, essential for regulating the extracellular bioavailability of TGFβ and assembly of elastic fibre proteins, fibrillin-1 and tropoelastin. LTBP4 mutations are linked...
6.
Woods S, Humphreys P, Bates N, Richardson S, Kuba S, Brooks I, et al.
Cells
. 2021 Apr;
10(4).
PMID: 33805168
The growth factor TGFβ and the mechanosensitive calcium-permeable cation channel TRPV4 are both important for the development and maintenance of many tissues. Although TRPV4 and TGFβ both affect core cellular...
7.
Ozsvar J, Yang C, Cain S, Baldock C, Tarakanova A, Weiss A
Front Bioeng Biotechnol
. 2021 Mar;
9:643110.
PMID: 33718344
Elastic fibers are an important component of the extracellular matrix, providing stretch, resilience, and cell interactivity to a broad range of elastic tissues. Elastin makes up the majority of elastic...
8.
Humphreys P, Woods S, Smith C, Bates N, Cain S, Lucas R, et al.
ACS Synth Biol
. 2020 Oct;
9(11):3067-3078.
PMID: 33084303
Bone morphogenetic proteins (BMPs) are members of the transforming growth factor β (TGFβ) superfamily and have crucial roles during development; including mesodermal patterning and specification of renal, hepatic, and skeletal...
9.
Singh M, Cain S, Baldock C
Methods Mol Biol
. 2019 Aug;
2043:137-155.
PMID: 31463909
Lentiviral systems have proven advantageous in the delivery and long-term integration of gene sequences into the genome of several cell types in vitro, in vivo, as well as in clinical...
10.
Godwin A, Singh M, Lockhart-Cairns M, Alanazi Y, Cain S, Baldock C
Matrix Biol
. 2019 Jun;
84:17-30.
PMID: 31226403
Fibrillin is a large evolutionarily ancient extracellular glycoprotein that assembles to form beaded microfibrils which are essential components of most extracellular matrices. Fibrillin microfibrils have specific biomechanical properties to endow...