Steven L Carroll
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Explore the profile of Steven L Carroll including associated specialties, affiliations and a list of published articles.
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78
Citations
3413
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Recent Articles
1.
Jenkins D, Turner-Ivey B, Fromm Longo J, Carroll S
J Vis Exp
. 2024 Jun;
(207).
PMID: 38829133
Patients with the autosomal dominant tumor susceptibility syndrome neurofibromatosis type 1 (NF1) commonly develop plexiform neurofibromas (PNs) that subsequently transform into highly aggressive malignant peripheral nerve sheath tumors (MPNSTs). Understanding...
2.
Aldecoa I, Barroeta I, Carroll S, Fortea J, Gilmore A, Ginsberg S, et al.
Alzheimers Dement
. 2024 Jan;
20(3):2262-2272.
PMID: 38270275
Individuals with Down syndrome (DS) have a partial or complete trisomy of chromosome 21, resulting in an increased risk for early-onset Alzheimer's disease (AD)-type dementia by early midlife. Despite ongoing...
3.
Turner-Ivey B, Fromm Longo J, Jenkins D, Guest S, Carroll S
J Vis Exp
. 2023 Sep;
(198).
PMID: 37677047
Malignant Peripheral Nerve Sheath Tumors (MPNSTs) are derived from Schwann cells or their precursors. In patients with the tumor susceptibility syndrome neurofibromatosis type 1 (NF1), MPNSTs are the most common...
4.
Black L, Longo J, Anderson J, Carroll S
Am J Pathol
. 2023 Jun;
193(9):1298-1318.
PMID: 37328102
Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive, currently untreatable Schwann cell-derived neoplasms with hyperactive mitogen-activated protein kinase and mammalian target of rapamycin signaling pathways. To identify potential therapeutic targets,...
5.
Doutt S, Fromm Longo J, Carroll S
Glia
. 2022 Nov;
71(3):742-757.
PMID: 36416236
Schwann cell-derived neoplasms known as malignant peripheral nerve sheath tumors (MPNSTs) are the most common malignancy and the leading cause of death in individuals with neurofibromatosis Type 1. Using genome-scale...
6.
Erben L, Welday J, Cronin M, Murphy R, Skirzewski M, Vullhorst D, et al.
J Neurochem
. 2022 May;
161(5):435-452.
PMID: 35523590
Neuregulins (NRGs) and their cognate neuronal receptor ERBB4, which is expressed in GABAergic and dopaminergic neurons, regulate numerous behaviors in rodents and have been identified as schizophrenia at-risk genes. ErbB4...
7.
Byrne J, Banaszak A, Carpenter J, Carroll S, Castelhano M, Espinal P, et al.
Biopreserv Biobank
. 2022 May;
21(1):111-113.
PMID: 35507966
No abstract available.
8.
Fromm Longo J, Carroll S
Adv Cancer Res
. 2022 Feb;
153:305-341.
PMID: 35101235
The RASopathies are a group of genetic diseases in which the Ras/MAPK signaling pathway is inappropriately activated as a result of mutations in genes encoding proteins within this pathway. As...
9.
Li P, Wu Y, Hamlett E, Goodwin A, Halushka P, Carroll S, et al.
Mol Ther
. 2022 Jan;
30(4):1451-1464.
PMID: 35038582
Brain pericytes regulate cerebral blood flow, maintain the integrity of the blood-brain barrier (BBB), and facilitate the removal of amyloid β (Aβ), which is critical to healthy brain activity. Pericyte...
10.
Weber S, Brossier N, Prechtl A, Barnes S, Wilson L, Brosius S, et al.
Cell Commun Signal
. 2021 Sep;
19(1):95.
PMID: 34530870
Background: Loss of the Ras GTPase-activating protein neurofibromin promotes nervous system tumor pathogenesis in patients with neurofibromatosis type 1 (NF1). Neurofibromin loss potentially hyperactivates classic Ras (H-Ras, N-Ras, K-Ras), M-Ras,...