Randall L Woltjer
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Explore the profile of Randall L Woltjer including associated specialties, affiliations and a list of published articles.
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82
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8161
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Recent Articles
1.
Silbert L, Roese N, Krajbich V, Hurworth J, Lahna D, Schwartz D, et al.
Alzheimers Dement
. 2024 Apr;
20(6):3839-3851.
PMID: 38629888
Introduction: Age-related magnetic resonance imaging (MRI) T2 white matter hyperintensities (WMHs) are common and associated with neurological decline. We investigated the histopathological underpinnings of MRI WMH and surrounding normal appearing...
2.
Mathews R, Setthavongsack N, Le-Cook A, Kaempf A, Loftis J, Woltjer R, et al.
Platelets
. 2023 Dec;
35(1):2290916.
PMID: 38099327
Platelets are core components of thrombi but their effect on thrombus burden during deep vein thrombosis (DVT) has not been fully characterized. We examined the role of thrombopoietin-altered platelet count...
3.
Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, et al.
medRxiv
. 2023 Jul;
PMID: 37461624
Limited ancestral diversity has impaired our ability to detect risk variants more prevalent in non-European ancestry groups in genome-wide association studies (GWAS). We constructed and analyzed a multi-ancestry GWAS dataset...
4.
Weston L, Bowman A, Osterberg V, Meshul C, Woltjer R, Unni V
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36499619
Alpha-synuclein (aSyn) is a 14 kD protein encoded by the SNCA gene that is expressed in vertebrates and normally localizes to presynaptic terminals and the nucleus. aSyn forms pathological intracellular...
5.
Wood P, Woltjer R
Front Aging Neurosci
. 2022 Aug;
14:981868.
PMID: 36004004
Ether glycerophospholipids (GPL) are involved in membrane fluidity and fusion. Vinyl-ether GPL are also conjectured to provide antioxidant capacity in the brain. The roles of these lipids in the processes...
6.
Beger A, Hauther K, Dudzik B, Woltjer R, Wood P
Front Mol Neurosci
. 2022 Jul;
15:835628.
PMID: 35782380
Human brain lipidomics have elucidated structural lipids and lipid signal transduction pathways in neurologic diseases. Such studies have traditionally sourced tissue exclusively from brain bank biorepositories, however, limited inventories signal...
7.
Beger A, Dudzik B, Woltjer R, Wood P
Metabolites
. 2022 Feb;
12(2).
PMID: 35208260
Sphingolipids constitute a complex class of bioactive lipids with diverse structural and functional roles in neural tissue. Lipidomic techniques continue to provide evidence for their association in neurological diseases, including...
8.
Iida M, Farrell K, Walker J, Richardson T, Marx G, Bryce C, et al.
Acta Neuropathol Commun
. 2021 Aug;
9(1):134.
PMID: 34353357
Primary age-related tauopathy (PART) is a form of Alzheimer-type neurofibrillary degeneration occurring in the absence of amyloid-beta (Aβ) plaques. While PART shares some features with Alzheimer disease (AD), such as...
9.
McGann J, Spinner M, Garg S, Mullendorff K, Woltjer R, Mandel G
J Neurosci
. 2021 Jul;
41(31):6582-6595.
PMID: 34210779
Early studies in mouse neurodevelopment led to the discovery of the RE1 Silencing Transcription Factor (REST) and its role as a master repressor of neuronal gene expression. Recently, REST was...
10.
Wood P, Hauther K, Scarborough J, Craney D, Dudzik B, Cebak J, et al.
Life (Basel)
. 2021 Apr;
11(5).
PMID: 33924945
Ceramides have been implicated in a number of disease processes. However, current means of evaluation with flow infusion analysis (FIA) have been limited primarily due to poor sensitivity within our...