Kevin A Roth
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Explore the profile of Kevin A Roth including associated specialties, affiliations and a list of published articles.
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94
Citations
6950
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Recent Articles
1.
Roth K
J Histochem Cytochem
. 2023 May;
71(5):289-290.
PMID: 37199234
This commentary reflects on the significance and impact of the highly cited companion article that was published in the in 1997 (Gijlswijk RPM et al. Fluorochrome-labeled Tyramides: Use in Immunocytochemistry...
2.
Hsiao S, Sireci A, Pendrick D, Freeman C, Fernandes H, Schwartz G, et al.
JCO Precis Oncol
. 2022 Jan;
4:1038-1048.
PMID: 35050771
Purpose: The routine use of large next-generation sequencing (NGS) pan-cancer panels is required to identify the increasing number of, but often uncommon, actionable alterations to guide therapy. Inconsistent coverage and...
3.
Bianchetti E, Bates S, Nguyen T, Siegelin M, Roth K
Cells
. 2021 Jul;
10(7).
PMID: 34209035
Glioblastoma is a high-grade glial neoplasm with a patient survival of 12-18 months. Therefore, the identification of novel therapeutic targets is an urgent need. RAB38 is a GTPase protein implicated...
4.
Crawford J, Aguero-Rosenfeld M, Aifantis I, Cadoff E, Cangiarella J, Cordon-Cardo C, et al.
Acad Pathol
. 2021 May;
8:23742895211006818.
PMID: 34013020
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2, created an unprecedented need for comprehensive laboratory testing of populations, in order to meet the needs of medical practice...
5.
Fromm Longo J, Brosius S, Znoyko I, Alers V, Jenkins D, Wilson R, et al.
Sci Rep
. 2021 Mar;
11(1):5690.
PMID: 33707600
Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive Schwann cell-derived neoplasms that occur sporadically or in patients with neurofibromatosis type 1 (NF1). Preclinical research on sporadic MPNSTs has been limited...
6.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
7.
Zanazzi G, Liechty B, Pendrick D, Krasnozhen-Ratush O, Snuderl M, Allen J, et al.
Cold Spring Harb Mol Case Stud
. 2020 Aug;
6(5).
PMID: 32839179
We report a case of a slow-growing, diffuse, infiltrating glioma in the right brainstem of a 9-yr-old boy. The tumor was negative by immunohistochemical staining for histone H3 K27M, BRAF...
8.
Zanazzi G, Pendrick D, Lin C, Higgins D, Bruce J, Roth K, et al.
J Neuropathol Exp Neurol
. 2020 Jul;
79(8):929-931.
PMID: 32667042
No abstract available.
9.
Fromm Longo J, Brosius S, Black L, Worley S, Wilson R, Roth K, et al.
Cell Commun Signal
. 2019 Jul;
17(1):74.
PMID: 31291965
Background: We have found that erbB receptor tyrosine kinases drive Ras hyperactivation and growth in NF1-null malignant peripheral nerve sheath tumors (MPNSTs). However, MPNSTs variably express multiple erbB receptors with...
10.
Karpel-Massler G, Ishida C, Bianchetti E, Zhang Y, Shu C, Tsujiuchi T, et al.
Nat Commun
. 2017 Oct;
8(1):1067.
PMID: 29057925
Certain gliomas often harbor a mutation in the activity center of IDH1 (R132H), which leads to the production of the oncometabolite 2-R-2-hydroxyglutarate (2-HG). In six model systems, including patient-derived stem...