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Steven J Greco

Explore the profile of Steven J Greco including associated specialties, affiliations and a list of published articles. Areas
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Articles 55
Citations 2140
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Recent Articles
1.
Greco S, Ayer S, Guiro K, Sinha G, Donnelly R, El-Far M, et al.
Aging (Albany NY) . 2021 Nov; 13(21):23981-24016. PMID: 34762598
This study addresses the potential to reverse age-associated morbidity by establishing methods to restore the aged hematopoietic system. Parabiotic animal models indicated that young secretome could restore aged tissues, leading...
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Sinha G, Ferrer A, Ayer S, El-Far M, Pamarthi S, Naaldijk Y, et al.
Life Sci Alliance . 2021 Jun; 4(7). PMID: 34078741
The challenge for treating breast cancer (BC) is partly due to long-term dormancy driven by cancer stem cells (CSCs) capable of evading immune response and resist chemotherapy. BC cells show...
3.
Gergues M, Ayer S, Morelli S, Greco S, Rameshwar P
Methods Mol Biol . 2021 Feb; 2224:195-202. PMID: 33606216
Mice with human hematopoietic system have become critical for research and preclinical studies. Mice with patient-derived xenografts of different tumors exist without human immune system. Answers can be addressed with...
4.
Gergues M, Nagula V, Bliss S, Eljarrah A, Ayer S, Gnanavel N, et al.
J Immunol . 2020 Jan; 204(4):879-891. PMID: 31924647
Hematopoiesis is tightly regulated by the bone marrow (BM) niche. The niche is robust, allowing for the return of hematopoietic homeostasis after insults such as infection. Hematopoiesis is partly regulated...
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Munoz J, Walker N, Mareedu S, Pamarthi S, Sinha G, Greco S, et al.
Front Pharmacol . 2019 Mar; 10:134. PMID: 30853911
Glioblastoma multiforme (GBM) is a fatal malignancy of the central nervous system, commonly associated with chemoresistance. The alkylating agent Temozolomide (TMZ) is the front-line chemotherapeutic agent and has undergone intense...
7.
Walker N, Elias M, Guiro K, Bhatia R, Greco S, Bryan M, et al.
Cell Death Dis . 2019 Jan; 10(2):59. PMID: 30683851
Breast cancer (BC) cells (BCCs) can retain cellular quiescence for decades, a phenomenon referred to as dormancy. BCCs show preference for the bone marrow (BM) where they can remain dormant...
8.
Bliss S, Paul S, Pobiarzyn P, Ayer S, Sinha G, Pant S, et al.
Sci Rep . 2018 Jan; 8(1):367. PMID: 29321622
This study proposes that a novel developmental hierarchy of breast cancer (BC) cells (BCCs) could predict treatment response and outcome. The continued challenge to treat BC requires stratification of BCCs...
9.
Walker N, Mourad Y, Liu K, Buxhoeveden M, Schoenberg C, Eloy J, et al.
Stem Cell Rev Rep . 2017 Jul; 13(5):644-658. PMID: 28733800
Orthotopic liver transplant (OLT) remains the standard of care for end stage liver disease. To circumvent allo-rejection, OLT subjects receive gluococorticoids (GC). We investigated the effects of GC on endogenous...
10.
Greco S, Yehia G, Potian J, Molina C, Rameshwar P
Stem Cell Rev Rep . 2016 Nov; 13(1):116-126. PMID: 27822872
Despite extensive insights on the interaction between hematopoietic stem cells (HSCs) and the supporting bone marrow (BM) stroma in hematopoietic homeostasis there remains unanswered questions on HSC regulation. We report...