Steven H Olson
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Explore the profile of Steven H Olson including associated specialties, affiliations and a list of published articles.
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38
Citations
908
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Recent Articles
1.
Reis P, Holec S, Ezeiruaku C, Frost M, Brown C, Liu S, et al.
J Parkinsons Dis
. 2025 Feb;
14(8):1543-1558.
PMID: 39957201
Background: Multiple system atrophy (MSA) and Parkinson's disease (PD) are caused by misfolded α-synuclein spreading throughout the central nervous system. While familial PD is linked to several α-synuclein mutations, no...
2.
Feng Y, Grotegut S, Jovanovic P, Gandin V, Olson S, Murad R, et al.
Front Pharmacol
. 2025 Jan;
15:1528449.
PMID: 39749209
[This corrects the article DOI: 10.3389/fphar.2022.1029093.].
3.
Moore M, Person K, Alwin A, Krusemark C, Foster N, Ray C, et al.
Res Sq
. 2024 Dec;
PMID: 39711540
G protein-coupled receptors (GPCRs), the largest family of drug targets, can signal through 16 subtypes of Gα proteins. Biased compounds that selectively activate therapy-relevant pathways promise to be safer, more...
4.
Moore M, Person K, Alwin A, Krusemark C, Foster N, Ray C, et al.
bioRxiv
. 2024 Nov;
PMID: 39605353
G protein-coupled receptors (GPCRs), the largest family of drug targets, can signal through 16 subtypes of Gα proteins. Biased compounds that selectively activate therapy-relevant pathways promise to be safer, more...
5.
Reis P, Holec S, Ezeiruaku C, Frost M, Brown C, Liu S, et al.
bioRxiv
. 2024 Jul;
PMID: 39026799
Multiple system atrophy (MSA) and Parkinson's disease (PD) are caused by misfolded -synuclein spreading throughout the central nervous system. While familial PD is linked to several point mutations in -synuclein,...
6.
Gereau G, Zhou D, Van Voorhies K, Tyler R, Campbell J, Murray J, et al.
bioRxiv
. 2024 Apr;
PMID: 38645173
Alcohol use disorders (AUDs) impose an enormous societal and financial burden, and world-wide, alcohol misuse is the 7 leading cause of premature death. Despite this, there are currently only 3...
7.
Feng Y, Grotegut S, Jovanovic P, Gandin V, Olson S, Murad R, et al.
Front Pharmacol
. 2022 Dec;
13:1029093.
PMID: 36532738
The translation initiation complex 4F (eIF4F) is a rate-limiting factor in protein synthesis. Alterations in eIF4F activity are linked to several diseases, including cancer and infectious diseases. To this end,...
8.
Holec S, Lee J, Oehler A, Batia L, Wiggins-Gamble A, Lau J, et al.
PLoS Pathog
. 2022 Dec;
18(12):e1010956.
PMID: 36454879
In multiple system atrophy (MSA), the α-synuclein protein misfolds into a self-templating prion conformation that spreads throughout the brain, leading to progressive neurodegeneration. While the E46K mutation in α-synuclein causes...
9.
Verma S, Crawford D, Khateb A, Feng Y, Sergienko E, Pathria G, et al.
Nat Cell Biol
. 2022 Sep;
24(9):1422-1432.
PMID: 36050469
Tumour dependency on specific metabolic signals has been demonstrated and often guided numerous therapeutic approaches. We identify melanoma addiction to the mitochondrial protein glutaryl-CoA dehydrogenase (GCDH), which functions in lysine...
10.
Holec S, Lee J, Oehler A, Ooi F, Mordes D, Olson S, et al.
Acta Neuropathol
. 2022 Aug;
144(4):677-690.
PMID: 36018376
In multiple system atrophy (MSA), the protein α-synuclein misfolds into a prion conformation that self-templates and causes progressive neurodegeneration. While many point mutations in the α-synuclein gene, SNCA, have been...