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Charles W Frevert

Explore the profile of Charles W Frevert including associated specialties, affiliations and a list of published articles. Areas
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Articles 88
Citations 3330
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Recent Articles
1.
Soucy A, Brune J, Jayaraman A, Shenoy A, Korkmaz F, Etesami N, et al.
JCI Insight . 2025 Feb; PMID: 39998887
The role of mesenchymal cells during respiratory infection is not well defined, including whether, which, and how the different types of mesenchymal cells respond. We collected all mesenchymal cells from...
2.
Chang M, Chan C, Brune J, Manicone A, Bomsztyk K, Frevert C, et al.
Am J Physiol Cell Physiol . 2024 Oct; 327(5):C1274-C1288. PMID: 39400584
Growing evidence supports a role for versican as an important component of the inflammatory response, with both pro- and anti-inflammatory roles depending on the specific context of the system or...
3.
Chang M, Chan C, Brune J, Manicone A, Bomsztyk K, Frevert C, et al.
bioRxiv . 2024 Apr; PMID: 38559011
Growing evidence supports a role for versican as an important component of the inflammatory response, with both pro- and anti-inflammatory roles depending on the specific context of the system or...
4.
Tang F, Reeves S, Brune J, Chang M, Chan C, Waldron P, et al.
Matrix Biol . 2024 Jan; 126:25-42. PMID: 38232913
The inter-alpha-trypsin inhibitor (IαI) complex is composed of the bikunin core protein with a single chondroitin sulfate (CS) attached and one or two heavy chains (HCs) covalently linked to the...
5.
Matthay M, Schmidt E, Bastarache J, Calfee C, Frevert C, Martin T
Am J Respir Crit Care Med . 2023 Dec; 209(5):488-490. PMID: 38091521
No abstract available.
6.
Chang M, Brune J, Black M, Altemeier W, Frevert C
Am J Physiol Lung Cell Mol Physiol . 2023 Aug; 325(4):L518-L535. PMID: 37581225
Studies of pulmonary inflammation require unique considerations due to the complex structure and composition of the lungs. The lungs have multiple compartments and diverse immune cell populations, with inherently high...
7.
Murphy R, Lai Y, Liu M, Al-Shaikhly T, Altman M, Altemeier W, et al.
Am J Respir Crit Care Med . 2023 May; 207(12):1565-1575. PMID: 37212596
Indirect airway hyperresponsiveness (AHR) is a highly specific feature of asthma, but the underlying mechanisms responsible for driving indirect AHR remain incompletely understood. To identify differences in gene expression in...
8.
Al-Shaikhly T, Murphy R, Lai Y, Frevert C, Debley J, Ziegler S, et al.
Respirology . 2023 Mar; 28(5):491-494. PMID: 36914406
No abstract available.
9.
Tang F, Brune J, Chang M, Reeves S, Altemeier W, Frevert C
Am J Physiol Cell Physiol . 2022 Jun; 323(2):C249-C276. PMID: 35649251
The extracellular matrix (ECM) imparts critical mechanical and biochemical information to cells in the lungs. Proteoglycans are essential constituents of the ECM and play a crucial role in controlling numerous...
10.
Gong K, Mikacenic C, Long M, Frevert C, Birkland T, Charron J, et al.
Am J Respir Cell Mol Biol . 2022 Feb; 66(5):555-563. PMID: 35157553
Acute respiratory distress syndrome (ARDS) remains a significant problem in need of new pharmaceutical approaches to improve its resolution. Studies comparing gene expression signatures in rodents and humans with lung...