Steven A Vokes
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Explore the profile of Steven A Vokes including associated specialties, affiliations and a list of published articles.
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35
Citations
1273
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Recent Articles
21.
Liu J, Li Q, Kuehn M, Litingtung Y, Vokes S, Chiang C
Dev Biol
. 2013 Jan;
375(2):160-71.
PMID: 23313125
Sonic hedgehog (Shh) signal, mediated by the Gli family of transcription factors, plays an essential role in the growth and patterning of the limb. Through analysis of the early limb...
22.
Momb J, Lewandowski J, Bryant J, Fitch R, Surman D, Vokes S, et al.
Proc Natl Acad Sci U S A
. 2012 Dec;
110(2):549-54.
PMID: 23267094
Maternal supplementation with folic acid is known to reduce the incidence of neural tube defects (NTDs) by as much as 70%. Despite the strong clinical link between folate and NTDs,...
23.
Rabinowitz A, Vokes S
Dev Biol
. 2012 Jun;
368(2):165-80.
PMID: 22683377
The developing limb is one of the best described vertebrate systems for understanding how coordinated gene expression during embryogenesis leads to the structures present in the mature organism. This knowledge,...
24.
Lee E, Ji H, Ouyang Z, Zhou B, Ma W, Vokes S, et al.
Proc Natl Acad Sci U S A
. 2010 May;
107(21):9736-41.
PMID: 20460306
Many genes initially identified for their roles in cell fate determination or signaling during development can have a significant impact on tumorigenesis. In the developing cerebellum, Sonic hedgehog (Shh) stimulates...
25.
Niakan K, Ji H, Maehr R, Vokes S, Rodolfa K, Sherwood R, et al.
Genes Dev
. 2010 Feb;
24(3):312-26.
PMID: 20123909
In embryonic stem (ES) cells, a well-characterized transcriptional network promotes pluripotency and represses gene expression required for differentiation. In comparison, the transcriptional networks that promote differentiation of ES cells and...
26.
Modeling the spatio-temporal network that drives patterning in the vertebrate central nervous system
Nishi Y, Ji H, Wong W, McMahon A, Vokes S
Biochim Biophys Acta
. 2009 May;
1789(4):299-305.
PMID: 19445894
In this review, we discuss the gene regulatory network underlying the patterning of the ventral neural tube during vertebrate embryogenesis. The neural tube is partitioned into domains of distinct cell...
27.
Vokes S, Ji H, Wong W, McMahon A
Genes Dev
. 2008 Oct;
22(19):2651-63.
PMID: 18832070
Sonic hedgehog (Shh) signals via Gli transcription factors to direct digit number and identity in the vertebrate limb. We characterized the Gli-dependent cis-regulatory network through a combination of whole-genome chromatin...
28.
Vokes S, Ji H, McCuine S, Tenzen T, Giles S, Zhong S, et al.
Development
. 2007 Apr;
134(10):1977-89.
PMID: 17442700
Sonic hedgehog (Shh) acts as a morphogen to mediate the specification of distinct cell identities in the ventral neural tube through a Gli-mediated (Gli1-3) transcriptional network. Identifying Gli targets in...
29.
Ji H, Vokes S, Wong W
Nucleic Acids Res
. 2006 Nov;
34(21):e146.
PMID: 17090591
Genome-wide location analysis (ChIP-chip, ChIP-PET) is a powerful technique to study mammalian transcriptional regulation. In order to obtain a basic understanding of the location data generated for mammalian transcription factors...
30.
Yuen C, Rodda S, Vokes S, McMahon A, Liu D
J Am Chem Soc
. 2006 Jul;
128(27):8939-46.
PMID: 16819890
Inteins are naturally occurring protein elements that catalyze their own excision from within a larger protein together with the ligation of the flanking "extein" sequences. Previously we reported the directed...