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Steve Peigneur

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Articles 193
Citations 1881
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Recent Articles
1.
Saggiomo S, Peigneur S, Tytgat J, Daly N, Wilson D
FEBS Open Bio . 2024 Nov; 15(3):399-414. PMID: 39563477
The stonefish Synanceia verrucosa and Synanceia horrida are arguably the most venomous fish species on earth and the culprits of severe stings in humans globally. Investigation into the venoms of...
2.
Pinheiro-Junior E, Alirahimi E, Peigneur S, Isensee J, Schiffmann S, Erkoc P, et al.
BMC Biol . 2024 Jul; 22(1):164. PMID: 39075558
Background: The identification of novel toxins from overlooked and taxonomically exceptional species bears potential for various pharmacological applications. The remipede Xibalbanus tulumensis, an underwater cave-dwelling crustacean, is the only crustacean...
3.
Seldeslachts A, Maurstad M, Oyen J, Undheim E, Peigneur S, Tytgat J
Cell Mol Life Sci . 2024 Jul; 81(1):311. PMID: 39066932
Lepidopterism, a skin inflammation condition caused by direct or airborne exposure to irritating hairs (setae) from processionary caterpillars, is becoming a significant public health concern. Recent outbreaks of the oak...
4.
Seldeslachts A, Undheim E, Vriens J, Tytgat J, Peigneur S
Cell Mol Life Sci . 2024 Jun; 81(1):281. PMID: 38940922
As human skin comes into contact with the tiny hairs or setae of the oak processionary caterpillar, Thaumetopoea processionea, a silent yet intense chemical confrontation occurs. The result is a...
5.
Peigneur S, Tibery D, Tytgat J
Membranes (Basel) . 2024 May; 14(5). PMID: 38786948
An insect neuroactive helix ring peptide called U-MYRTX-Tb1a (abbreviated as U) from the venom of the ant, . U is a 34-amino-acid peptide that is claimed to be one of...
6.
Joukhan A, Kononenko V, Bele T, Dolenc M, Peigneur S, Pinheiro-Junior E, et al.
Mar Drugs . 2024 Apr; 22(4). PMID: 38667764
Nicotine binds to nicotinic acetylcholine receptors (nAChRs) that are overexpressed in different cancer cells, promoting tumor growth and resistance to chemotherapy. In this study, we aimed to investigate the potential...
7.
Zavarzina I, Kuzmenkov A, Dobrokhotov N, Maleeva E, Korolkova Y, Peigneur S, et al.
FEBS Lett . 2024 Apr; 598(8):889-901. PMID: 38563123
BeKm-1 is a peptide toxin from scorpion venom that blocks the pore of the potassium channel hERG (K11.1) in the human heart. Although individual protein structures have been resolved, the...
8.
An D, Carrazoni G, Neves B, DHooge R, Peigneur S, Tytgat J
Biomedicines . 2024 Feb; 12(2). PMID: 38398056
Cannabinoid receptors (CB1 and CB2) are promising targets for a better understanding of neurological diseases. Nevertheless, only a few ligands of CB have reached clinical application so far. Venoms are...
9.
Seldeslachts A, Peigneur S, Tytgat J
Membranes (Basel) . 2023 Dec; 13(12). PMID: 38132901
Histamine receptors (HRs) are G-protein-coupled receptors involved in diverse responses triggered by histamine release during inflammation or by encounters with venomous creatures. Four histamine receptors (H1R-H4R) have been cloned and...
10.
Mineev K, Chernykh M, Motov V, Prudnikova D, Pavlenko D, Kuzmenkov A, et al.
FEBS Lett . 2023 Jul; 597(18):2358-2368. PMID: 37501371
Scorpion α-toxins (α-NaTx) inhibiting the inactivation of voltage-gated sodium channels (Na ) are a well-studied family of small proteins. We previously showed that the structure of α-NaTx specificity module responsible...