Stephen P Faux
Overview
Explore the profile of Stephen P Faux including associated specialties, affiliations and a list of published articles.
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10
Citations
436
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Recent Articles
1.
Breheny D, Oke O, Faux S
Altern Lab Anim
. 2011 Jul;
39(3):233-55.
PMID: 21777038
Carcinogenesis is a highly complex, multi-stage process that can occur over a relatively long period before its clinical manifestation. While the sequence in which a cancer cell acquires the necessary...
2.
Shukla A, Barrett T, MacPherson M, Hillegass J, Fukagawa N, Swain W, et al.
Am J Respir Cell Mol Biol
. 2011 Apr;
45(5):906-14.
PMID: 21454801
We hypothesized that normal human mesothelial cells acquire resistance to asbestos-induced toxicity via induction of one or more epidermal growth factor receptor (EGFR)-linked survival pathways (phosphoinositol-3-kinase/AKT/mammalian target of rapamycin and...
3.
The role of oxidative stress in the biological responses of lung epithelial cells to cigarette smoke
Faux S, Tai T, Thorne D, Xu Y, Breheny D, Gaca M
Biomarkers
. 2009 Jul;
14 Suppl 1:90-6.
PMID: 19604067
The mechanism(s) by which cigarette smoke contributes to lung diseases, such as cancer, remains unclear. Recent developments in our knowledge of cell signalling events suggest that cigarette smoke causes oxidative...
4.
Fearon I, Faux S
J Mol Cell Cardiol
. 2009 Jun;
47(3):372-81.
PMID: 19481547
Cardiovascular disease is the most common cause of mortality in the Western world and accounts for up to a third of all deaths worldwide. Cardiovascular disease is multifactorial and involves...
5.
Kumaravel T, Vilhar B, Faux S, Jha A
Cell Biol Toxicol
. 2007 Nov;
25(1):53-64.
PMID: 18040874
The Comet Assay or single cell gel electrophoresis assay is one of the very widely used assays to microscopically detect DNA damage at the level of a single cell. The...
6.
Swain W, OByrne K, Faux S
Am J Physiol Lung Cell Mol Physiol
. 2003 Nov;
286(4):L859-65.
PMID: 14617514
Asbestos fibers are biopersistent particles that are capable of stimulating chronic inflammatory responses in the pleura of exposed individuals. Exposure of pleural mesothelial cells, the progenitor cell of malignant mesothelioma,...
7.
Donaldson K, Stone V, Borm P, Jimenez L, Gilmour P, Schins R, et al.
Free Radic Biol Med
. 2003 May;
34(11):1369-82.
PMID: 12757847
This review focuses on the potential role that oxidative stress plays in the adverse effects of PM(10). The central hypothesis is that the ability of PM(10) to cause oxidative stress...
8.
Wickenden J, Clarke M, Rossi A, Rahman I, Faux S, Donaldson K, et al.
Am J Respir Cell Mol Biol
. 2003 May;
29(5):562-70.
PMID: 12748058
Emphysema is characterized by enlargement of the distal airspaces in the lungs due to destruction of alveolar walls. Alveolar endothelial and epithelial cell apoptosis induced by cigarette smoke is thought...
9.
Beddowes E, Faux S, Chipman J
Toxicology
. 2003 Apr;
187(2-3):101-15.
PMID: 12699900
Chemical carcinogens are generally classified as genotoxic or non-genotoxic. However, weak genotoxicity at high concentrations is sometimes observed and interpretation is often problematic. In addition, certain rodent carcinogens exert their...
10.
Edwards J, Faux S, Plummer S, Abrams K, Walker R, Waller D, et al.
Clin Cancer Res
. 2002 Jun;
8(6):1857-62.
PMID: 12060628
Malignant mesothelioma (MM) is a fatal tumor of increasing incidence, which is resistant to current therapy. Cyclooxygenase-2 (COX-2) plays an important role in solid tumor growth, invasiveness, and angiogenesis, in...