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David Thorne

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Articles 52
Citations 650
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Recent Articles
1.
Thorne D, McHugh D, Simms L, Lee K, Fujimoto H, Moses S, et al.
Front Toxicol . 2024 Aug; 6:1460271. PMID: 39100892
[This corrects the article DOI: 10.3389/ftox.2024.1376118.].
2.
Thorne D, McHugh D, Simms L, Lee K, Fujimoto H, Moses S, et al.
Front Toxicol . 2024 Jun; 6:1376118. PMID: 38938663
toxicology research has accelerated with the use of , computational approaches and human tissue systems, facilitating major improvements evaluating the safety and health risks of novel consumer products. Innovation in...
3.
Yu F, Bishop E, Miazzi F, Evans R, Smart D, Breheny D, et al.
Mutat Res Genet Toxicol Environ Mutagen . 2024 Apr; 895:503738. PMID: 38575247
'Modern' oral tobacco-free nicotine pouches (NPs) are a nicotine containing product similar in appearance and concept to Swedish snus. A three-step approach was taken to analyse the biological effects of...
4.
Crooks I, Thorne D, West M, Prasad K, Gray A, West C, et al.
Food Chem Toxicol . 2024 Mar; 187:114583. PMID: 38518883
Any functional change in cigarette filter design warrants a rigorous assessment to ensure comparability to existing filter functionality. This study compares the functionality of a standard CA filter with a...
5.
Crooks I, Clements J, Curren R, Guo X, Hollings M, Lloyd M, et al.
Altern Lab Anim . 2023 Dec; 52(1):42-59. PMID: 38055860
The Institute for In Vitro Sciences (IIVS) is sponsoring a series of workshops to develop recommendations for optimal scientific and technical approaches for conducting assays to assess potential toxicity within...
6.
Bishop E, Gaca M, Thorne D
Drug Test Anal . 2023 Mar; 15(10):1133-1144. PMID: 36945752
Electronic-cigarette regulation and risk assessment is a prominent and developing field, as the popularity and prevalence of this product category increases. Over the last 10 years since their emergence, there...
7.
Moore M, Abraham I, Ballantyne M, Behrsing H, Cao X, Clements J, et al.
Altern Lab Anim . 2023 Feb; 51(1):55-79. PMID: 36821083
The Institute for In Vitro Sciences (IIVS) is sponsoring a series of workshops to identify, discuss and develop recommendations for optimal scientific and technical approaches for conducting assays, to assess...
8.
Goodall S, Gale N, Thorne D, Hadley S, Prasad K, Gilmour I, et al.
Toxicol Rep . 2022 Dec; 9:1426-1442. PMID: 36561950
Background: Tobacco Heating Products (THPs) are tobacco products that heat rather than burn tobacco with temperatures less than 350 °C. Because of this operating principle, they produce substantially fewer and...
9.
Behrsing H, Wahab A, Ukishima L, Grodi C, Frentzel S, Johne S, et al.
Altern Lab Anim . 2022 Aug; 50(4):293-309. PMID: 35938181
The use of reconstituted human airway (RHuA) epithelial tissues to assess functional endpoints is highly relevant in respiratory toxicology, but standardised methods are lacking. In June 2015, the Institute for...
10.
Crooks I, Hollings M, Leverette R, Jordan K, Breheny D, Moore M, et al.
Mutat Res Genet Toxicol Environ Mutagen . 2022 Aug; 879-880:503502. PMID: 35914858
No cigarette smoke test matrix is without limitation, due to the complexity of the starting aerosol and phase to phase dynamics. It is impossible to capture all chemicals at the...