Stephen P Bell
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Explore the profile of Stephen P Bell including associated specialties, affiliations and a list of published articles.
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Articles
69
Citations
4483
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Recent Articles
1.
Barker J, Murray A, Bell S
G3 (Bethesda)
. 2025 Jan;
15(2).
PMID: 39804723
Evidence suggests that increases in ploidy have occurred frequently in the evolutionary history of organisms and can serve adaptive functions to specialized somatic cells in multicellular organisms. However, the sudden...
2.
Zhou X, Weng S, Bell S, Amon A
Proc Natl Acad Sci U S A
. 2024 Oct;
121(45):e2413873121.
PMID: 39475649
In the budding yeast , exit from mitosis is coupled to spindle position to ensure successful genome partitioning between mother and daughter cells. This coupling occurs through a GTPase signaling...
3.
Zhou X, Weng S, Bell S, Amon A
bioRxiv
. 2024 May;
PMID: 38798491
In the budding yeast , exit from mitosis is coupled to spindle position to ensure successful genome partitioning between mother and daughter cell. This coupling occurs through a GTPase signaling...
4.
Pike A, Friend C, Bell S
Nucleic Acids Res
. 2023 Sep;
51(19):10506-10518.
PMID: 37739410
Replication protein A (RPA) binds single-stranded DNA (ssDNA) and serves critical functions in eukaryotic DNA replication, the DNA damage response, and DNA repair. During DNA replication, RPA is required for...
5.
Ye B, Bradshaw A, Abrahante J, Dragon J, Haussler T, Bell S, et al.
Circ Heart Fail
. 2023 Aug;
16(8):e010395.
PMID: 37582166
Background: Heart failure with preserved ejection fraction (HFpEF) is increasingly prevalent and has few treatments. The molecular mechanisms and resultant signaling pathways that underlie the development of HFpEF are poorly...
6.
Zhang A, Friedman L, Gelles J, Bell S
Proc Natl Acad Sci U S A
. 2023 Jul;
120(30):e2305556120.
PMID: 37463200
During origin licensing, the eukaryotic replicative helicase Mcm2-7 forms head-to-head double hexamers to prime origins for bidirectional replication. Recent single-molecule and structural studies revealed that one molecule of the helicase...
7.
Amasino A, Gupta S, Friedman L, Gelles J, Bell S
Proc Natl Acad Sci U S A
. 2023 Jul;
120(29):e2221484120.
PMID: 37428921
Eukaryotic DNA replication must occur exactly once per cell cycle to maintain cell ploidy. This outcome is ensured by temporally separating replicative helicase loading (G1 phase) and activation (S phase)....
8.
Zhang A, Friedman L, Gelles J, Bell S
bioRxiv
. 2023 Jul;
PMID: 37398123
Significance Statement: Bidirectional DNA replication, in which two replication forks travel in opposite directions from each origin of replication, is required for complete genome duplication. To prepare for this event,...
9.
Amasino A, Gupta S, Friedman L, Gelles J, Bell S
bioRxiv
. 2023 Jan;
PMID: 36711604
Significance Statement: Each time a eukaryotic cell divides (by mitosis) it must duplicate its chromosomal DNA exactly once to ensure that one full copy is passed to each resulting cell....
10.
Wakefield J, Bell S, Palmer B
Front Physiol
. 2022 Sep;
13:980662.
PMID: 36171969
Myocardial relaxation in late systole is enhanced by increasing velocities of lengthening. Given that inorganic phosphate (Pi) can rebind to the force-producing myosin enzyme prior to MgADP release and hasten...