Stephen J Vanner
Overview
Explore the profile of Stephen J Vanner including associated specialties, affiliations and a list of published articles.
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Articles
58
Citations
1689
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Recent Articles
1.
Aguilera-Lizarraga J, Lopez-Lopez C, Jaramillo-Polanco J, Florens M, Yu Y, Tsang Q, et al.
Gastroenterology
. 2025 Feb;
PMID: 39978560
Background & Aims: We recently showed that a bacterial infection can break oral tolerance to food and lead to IgE-dependent mast cell activation and food-induced abdominal pain, which could constitute...
2.
Degro C, Jimenez-Vargas N, Guzman-Rodriguez M, Schincariol H, Tsang Q, Reed D, et al.
Br J Pharmacol
. 2024 Oct;
182(3):581-595.
PMID: 39396524
Background And Purpose: Tolerance to the analgesic effects of opioids and resultant dose escalation is associated with worsening of side effects and greater addiction risk. Here, we compare the development...
3.
Baker C, Sessenwein J, Wood H, Yu Y, Tsang Q, Alward T, et al.
Cell Mol Gastroenterol Hepatol
. 2024 Mar;
18(4):101334.
PMID: 38494056
Background & Aims: Abdominal pain is a major symptom of diseases that are associated with microbial dysbiosis, including irritable bowel syndrome and inflammatory bowel disease. Germ-free mice are more prone...
4.
Douchant K, He S, Noordhof C, Greenlaw J, Vancuren S, Schroeter K, et al.
Commun Biol
. 2024 Jan;
7(1):135.
PMID: 38280981
Clostridioides difficile is the leading cause of antibiotic-associated infectious diarrhea. The development of C.difficile infection is tied to perturbations of the bacterial community in the gastrointestinal tract, called the gastrointestinal...
5.
Degro C, Jimenez-Vargas N, Tsang Q, Yu Y, Guzman-Rodriguez M, Alizadeh E, et al.
Pain
. 2023 Jun;
164(11):2501-2515.
PMID: 37326658
Targeting the acidified inflammatory microenvironment with pH-sensitive opioids is a novel approach for managing visceral pain while mitigating side effects. The analgesic efficacy of pH-dependent opioids has not been studied...
6.
Brant B, Yu Y, Omar A, Jaramillo Polanco J, Lopez Lopez C, Jimenez Vargas N, et al.
Neurogastroenterol Motil
. 2023 May;
35(9):e14596.
PMID: 37248774
Background: Monosodium glutamate (MSG) has been identified as a trigger of abdominal pain in irritable bowel syndrome (IBS), but the mechanism is unknown. This study examined whether MSG causes visceral...
7.
Rodrigues D, Poitras P, Day A, Sperber A, Palsson O, Bangdiwala S, et al.
Neurogastroenterol Motil
. 2023 Mar;
35(6):e14585.
PMID: 36989173
Background: Using data from the Rome Foundation Global Epidemiology Study examining prevalence of disorders of gut-brain interaction (DGBI) in 33 countries, this study explored the prevalence of all 22 disorders...
8.
Tuck C, Omar A, Palma G, Osman S, Jimenez-Vargas N, Yu Y, et al.
Gut
. 2023 Jan;
PMID: 36591617
Objective: Dietary therapies for irritable bowel syndrome (IBS) have received increasing interest but predicting which patients will benefit remains a challenge due to a lack of mechanistic insight. We recently...
9.
Palma G, Shimbori C, Reed D, Yu Y, Rabbia V, Lu J, et al.
Sci Transl Med
. 2022 Jul;
14(655):eabj1895.
PMID: 35895832
The gut microbiota has been implicated in chronic pain disorders, including irritable bowel syndrome (IBS), yet specific pathophysiological mechanisms remain unclear. We showed that decreasing intake of fermentable carbohydrates improved...
10.
Yu Y, Tsang Q, Jaramillo-Polanco J, Lomax A, Vanner S, Reed D
J Neurosci
. 2022 Jul;
42(33):6313-6324.
PMID: 35790401
While effective in treating abdominal pain, opioids have significant side effects. Recent legalization of cannabis will likely promote use of cannabinoids as an adjunct or alternative to opioids, despite a...