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Stephen J Iturria

Explore the profile of Stephen J Iturria including associated specialties, affiliations and a list of published articles. Areas
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Citations 178
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Recent Articles
1.
Chalmers M, Pascal B, Willis S, Zhang J, Iturria S, Dodge J, et al.
Int J Mass Spectrom . 2011 Apr; 302(1-3):59-68. PMID: 21528013
Hydrogen/deuterium exchange (HDX) mass spectrometry has been widely applied to the characterization of protein dynamics. More recently, differential HDX has been shown to be effective for the characterization of ligand...
2.
Iturria S
Pharm Stat . 2010 Jun; 10(2):169-74. PMID: 20572260
A method is proposed for block randomization of treatments to experimental units that can accommodate both multiple quantitative blocking variables and unbalanced designs. Hierarchical clustering in conjunction with leaf-order optimization...
3.
Ma Y, Khalifa B, Yee Y, Lu J, Memezawa A, Savkur R, et al.
J Clin Invest . 2006 Mar; 116(4):892-904. PMID: 16528410
Vitamin D receptor (VDR) ligands are therapeutic agents for the treatment of psoriasis, osteoporosis, and secondary hyperparathyroidism. VDR ligands also show immense potential as therapeutic agents for autoimmune diseases and...
4.
Iturria S
J Biopharm Stat . 2005 Mar; 15(2):343-51. PMID: 15796299
The analysis of dose-response assays measuring two correlated responses is considered. Attention is given to statistical inference for the potency ratio. Results from a simulation study suggest that a post...
5.
Olson J, Sellers T, Iturria S, Hartmann L
Cancer Detect Prev . 2004 Nov; 28(5):357-60. PMID: 15542261
Purpose: We investigated whether removal of the ovaries is an appropriate risk reduction option for women at elevated risk of breast cancer based on family history of breast cancer. Patients...
6.
Slager S, Iturria S
BMC Genet . 2004 Feb; 4 Suppl 1:S13. PMID: 14975081
Problem 1 of the Genetic Analysis Workshop 13(GAW13) contains longitudinal data of cardiovascular measurements from 330 pedigrees. The longitudinal data complicates the phenotype definition because multiple measurements are taken on...
7.
Peethambaram P, Cliby W, Lubiniecki G, Clayton A, Roche P, Iturria S, et al.
Gynecol Oncol . 2003 Apr; 89(1):99-104. PMID: 12694661
Objective: Our objective was to determine if the level of Her-2/neu expression in advanced ovarian cancer changed after platinum-based chemotherapy. Methods: Tissue samples from 43 patients who had surgery for...
8.
Jelinek D, Tschumper R, Stolovitzky G, Iturria S, Tu Y, Lepre J, et al.
Mol Cancer Res . 2003 Mar; 1(5):346-61. PMID: 12651908
B-chronic lymphocytic leukemia (B-CLL) is an adult-onset leukemia characterized by significant accumulation of apoptosis-resistant monoclonal B lymphocytes. In this study, we performed gene expression profiling on B cells obtained from...
9.
Reinholz M, Iturria S, Ingle J, Roche P
Breast Cancer Res Treat . 2002 Sep; 74(3):255-69. PMID: 12206515
Several cytokines including members of the transforming growth factor-beta (TGF-beta) and tumor necrosis factor (TNF) families have been implicated in the homing mechanism of breast cancer metastasis. We hypothesize that...
10.
Calhoun E, McGovern R, Janney C, Cerhan J, Iturria S, Smith D, et al.
Clin Chem . 2002 Jul; 48(8):1218-24. PMID: 12142377
Background: The natural history of cervical cancer comprises a latency period that probably involves long-term immunologic tolerance of human papillomavirus infection. Identifying host determinants of viral persistence may help to...