Michael J Chalmers
Overview
Explore the profile of Michael J Chalmers including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
66
Citations
3242
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Bourner L, Chung L, Long H, Mcgettrick A, Xiao J, Roth K, et al.
Cell Rep
. 2024 Aug;
43(8):114570.
PMID: 39093697
A wide variety of electrophilic derivatives of itaconate, the Kreb's cycle-derived metabolite, are immunomodulatory, yet these derivatives have overlapping and sometimes contradictory activities. Therefore, we generated a genetic system to...
2.
Hudgens J, Gallagher E, Karageorgos I, Anderson K, Huang R, Chen G, et al.
J Res Natl Inst Stand Technol
. 2021 Dec;
124:1-7.
PMID: 34877153
No abstract available.
3.
Espada A, Haro R, Castanon J, Sayago C, Perez-Cozar F, Cano L, et al.
J Am Soc Mass Spectrom
. 2019 Nov;
30(12):2580-2583.
PMID: 31724102
Hydrogen/deuterium exchange mass spectrometry (HDX-MS) is a biophysical technique well suited to the characterization of protein dynamics and protein-ligand interactions. In order to accurately define the rate of exchange, HDX...
4.
Hudgens J, Gallagher E, Karageorgos I, Anderson K, Filliben J, Huang R, et al.
Anal Chem
. 2019 May;
91(11):7336-7345.
PMID: 31045344
Hydrogen-deuterium exchange mass spectrometry (HDX-MS) is an established, powerful tool for investigating protein-ligand interactions, protein folding, and protein dynamics. However, HDX-MS is still an emergent tool for quality control of...
5.
Sayago C, Gonzalez Valcarcel I, Qian Y, Lee J, Alsina-Fernandez J, Fite N, et al.
ACS Med Chem Lett
. 2018 Sep;
9(9):912-916.
PMID: 30258540
Molecular characterization of the binding epitope of IL-23R and its cognate cytokine IL-23 is paramount to understand the role in autoimmune diseases and to support the discovery of new inhibitors...
6.
Wijeratne A, Xiao J, Reutter C, Furness K, Leon R, Zia-Ebrahimi M, et al.
ACS Med Chem Lett
. 2018 Jun;
9(6):557-562.
PMID: 29937982
The KRASG12C protein product is an attractive, yet challenging, target for small molecule inhibition. One option for therapeutic intervention is to design small molecule ligands capable of binding to and...
7.
Ting J, Tung F, Antonysamy S, Wasserman S, Jones S, Zhang F, et al.
PLoS One
. 2018 Jan;
13(1):e0190850.
PMID: 29329326
To date, IL-17A antibodies remain the only therapeutic approach to correct the abnormal activation of the IL-17A/IL-17R signaling complex. Why is it that despite the remarkable success of IL-17 antibodies,...
8.
Zheng J, Chang M, Stites R, Wang Y, Bruning J, Pascal B, et al.
Nat Commun
. 2017 Oct;
8(1):923.
PMID: 29030554
The vitamin D receptor/retinoid X receptor-α heterodimer (VDRRXRα) regulates bone mineralization via transcriptional control of osteocalcin (BGLAP) gene and is the receptor for 1α,25-dihydroxyvitamin D (1,25D3). However, supra-physiological levels of...
9.
Saltzberg D, Broughton H, Pellarin R, Chalmers M, Espada A, Dodge J, et al.
J Phys Chem B
. 2016 Nov;
121(15):3493-3501.
PMID: 27807976
Characterization of interactions between proteins and other molecules is crucial for understanding the mechanisms of action of biological systems and, thus, drug discovery. An increasingly useful approach to mapping these...
10.
Darrah E, Kim A, Zhang X, Boronina T, Cole R, Fava A, et al.
J Proteome Res
. 2016 Oct;
16(1):355-365.
PMID: 27700100
Proteolysis of autoantigens can alter normal MHC class II antigen processing and has been implicated in the induction of autoimmune diseases. Many autoantigens are substrates for the protease granzyme B...