Stephen G Emerson
Overview
Explore the profile of Stephen G Emerson including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
2009
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Recent Articles
1.
Schwartz M, Emerson S, Punt J, Goff W
Aging Dis
. 2020 Aug;
11(4):742-745.
PMID: 32765940
Aging, type 2 diabetes, and male gender are major risk factors leading to increased COVID-19 morbidity and mortality. Thymic production and the export of naïve T cells decrease with aging...
2.
Mumau M, Vanderbeck A, Lynch E, Golec S, Emerson S, Punt J
J Immunol
. 2017 Dec;
200(3):1078-1087.
PMID: 29282309
The developmental fate of hematopoietic stem and progenitor cells is influenced by their physiological context. Although most hematopoietic stem and progenitor cells are found in the bone marrow of the...
3.
Moy R, Huffman A, Richman L, Crisalli L, Wang X, Hoxie J, et al.
Blood
. 2017 Jan;
129(7):906-916.
PMID: 28057639
Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Lymphocyte trafficking via chemokine receptors such as CCR5 plays a critical role...
4.
Oberg J, Glade Bender J, Sulis M, Pendrick D, Sireci A, Hsiao S, et al.
Genome Med
. 2016 Dec;
8(1):133.
PMID: 28007021
Background: Molecular characterization has the potential to advance the management of pediatric cancer and high-risk hematologic disease. The clinical integration of genome sequencing into standard clinical practice has been limited...
5.
Hexner E, Luger S, Reshef R, Jeschke G, Mangan J, Frey N, et al.
Am J Hematol
. 2016 Feb;
91(5):453-60.
PMID: 26858124
Limited cell numbers in umbilical cord blood (UCB) grafts present a major impediment to favorable outcomes in adult transplantation, largely related to delayed or failed engraftment. The advent of UCB...
6.
Land R, Rayne A, Vanderbeck A, Barlowe T, Manjunath S, Gross M, et al.
Stem Cells
. 2014 Oct;
33(1):278-88.
PMID: 25284014
Hematopoiesis is maintained throughout life by self-renewing hematopoietic stem cells (HSCs) that differentiate to produce both myeloid and lymphoid cells. The NR4A family of orphan nuclear receptors, which regulates cell...
7.
Singh L, Brennan T, Kim J, Egan K, McMillan E, Chen Q, et al.
Stem Cells
. 2012 Nov;
31(3):607-11.
PMID: 23193076
Age-related osteoporosis is characterized by a decrease in bone-forming capacity mediated by defects in the number and function of osteoblasts. An important cellular mechanism that may in part explain osteoblast...
8.
Domashenko A, Wiener S, Emerson S
Methods Mol Biol
. 2012 Aug;
916:303-16.
PMID: 22914950
The clinical potential of therapeutic quantities of primary hematopoietic cells, either unmodified or altered via genetic modification, has stimulated the search for techniques that allow the production of large numbers...
9.
Reshef R, Luger S, Hexner E, Loren A, Frey N, Nasta S, et al.
N Engl J Med
. 2012 Jul;
367(2):135-45.
PMID: 22784116
Background: Graft-versus-host disease (GVHD) is a major barrier to successful allogeneic hematopoietic stem-cell transplantation (HSCT). The chemokine receptor CCR5 appears to play a role in alloreactivity. We tested whether CCR5...
10.
Bungartz G, Land H, Scadden D, Emerson S
Blood
. 2011 Nov;
119(6):1380-9.
PMID: 22072554
HSC function depends on the tight control of proliferation and the balance between self-renewal and differentiation. Here, we report that the trimeric transcription factor NF-Y is critical for the survival...