Stephen D Bell
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Explore the profile of Stephen D Bell including associated specialties, affiliations and a list of published articles.
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97
Citations
3364
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Recent Articles
1.
Pilatowski-Herzing E, Samson R, Takemata N, Badel C, Bohall P, Bell S
Mol Microbiol
. 2024 Feb;
123(2):101-108.
PMID: 38404013
While there is a considerable body of knowledge regarding the molecular and structural biology and biochemistry of archaeal information processing machineries, far less is known about the nature of the...
2.
Badel C, Bell S
Nat Microbiol
. 2023 Dec;
9(1):263-273.
PMID: 38110698
Proteins in the structural maintenance of chromosomes (SMC) superfamily play key roles in chromosome organization and are ubiquitous across all domains of life. However, SMC proteins are notably absent in...
3.
Bell S
Biochem Soc Trans
. 2022 Dec;
50(6):1931-1939.
PMID: 36511238
A key maxim in modernist architecture is that 'form follows function'. While modernist buildings are hopefully the product of intelligent design, the architectures of chromosomes have been sculpted by the...
4.
Badel C, Samson R, Bell S
Nat Microbiol
. 2022 May;
7(6):820-830.
PMID: 35618771
In all organisms, the DNA sequence and the structural organization of chromosomes affect gene expression. The extremely thermophilic crenarchaeon Sulfolobus has one circular chromosome with three origins of replication. We...
5.
Greci M, Dooher J, Bell S
Nat Commun
. 2022 Jan;
13(1):433.
PMID: 35064114
Replicative DNA polymerases cannot initiate DNA synthesis de novo and rely on dedicated RNA polymerases, primases, to generate a short primer. This primer is then extended by the DNA polymerase....
6.
Takemata N, Bell S
STAR Protoc
. 2021 Jun;
2(2):100576.
PMID: 34142100
Chromosome organization in archaea has long been enigmatic due, in part, to the typically small cell size of archaea and the extremophilic nature of many of the model archaeal species...
7.
Takemata N, Bell S
STAR Protoc
. 2021 Jun;
2(2):100562.
PMID: 34113850
Chromosome conformation capture (3C) techniques are emerging as promising approaches to study genome organization in Archaea, the least understood domain of life in terms of chromosome biology. Here, we describe...
8.
Bohall P, Bell S
Front Microbiol
. 2021 May;
12:666974.
PMID: 33968003
Across the three domains of life, B-family DNA polymerases play a variety of roles in both DNA repair and DNA replication processes. We examine the phenotypic consequences of loss of...
9.
Takemata N, Bell S
Mol Cell
. 2020 Dec;
81(3):473-487.e6.
PMID: 33382983
Chromosome conformation capture (3C) technologies have identified topologically associating domains (TADs) and larger A/B compartments as two salient structural features of eukaryotic chromosomes. These structures are sculpted by the combined...
10.
Greci M, Bell S
Annu Rev Microbiol
. 2020 Jun;
74:65-80.
PMID: 32503372
It is now well recognized that the information processing machineries of archaea are far more closely related to those of eukaryotes than to those of their prokaryotic cousins, the bacteria....