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Stephen C Jameson

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Articles 151
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Recent Articles
21.
Peng C, Huggins M, Wanhainen K, Knutson T, Lu H, Georgiev H, et al.
Immunity . 2021 Dec; 55(1):98-114.e5. PMID: 34932944
Elevated gene expression of the costimulatory receptor Icos is a hallmark of CD8 tissue-resident memory (Trm) T cells. Here, we examined the contribution of ICOS in Trm cell differentiation. Upon...
22.
Kelekar A, Jameson S
Cell Metab . 2021 Dec; 33(12):2305-2306. PMID: 34879235
The metabolic state of T cells strongly influences their effector function and anti-tumor efficacy. St. Paul et al. (2021) report that Tc22, a CD8 T cell subset with potent anti-tumor...
23.
Evrard M, Wynne-Jones E, Peng C, Kato Y, Christo S, Fonseca R, et al.
J Exp Med . 2021 Oct; 219(1). PMID: 34677611
Tissue-resident memory T (TRM) cells provide long-lasting immune protection. One of the key events controlling TRM cell development is the local retention of TRM cell precursors coupled to downregulation of...
24.
Block K, Jameson S
Nat Immunol . 2021 Jul; 22(8):942-944. PMID: 34267376
No abstract available.
25.
Camell C, Yousefzadeh M, Zhu Y, Langhi Prata L, Huggins M, Pierson M, et al.
Science . 2021 Jun; 373(6552). PMID: 34103349
The COVID-19 pandemic has revealed the pronounced vulnerability of the elderly and chronically ill to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced morbidity and mortality. Cellular senescence contributes to inflammation,...
26.
Truckenbrod E, Burrack K, Knutson T, Borges da Silva H, Block K, OFlanagan S, et al.
Elife . 2021 Apr; 10. PMID: 33929324
Self-specific CD8T cells can escape clonal deletion, but the properties and capabilities of such cells in a physiological setting are unclear. We characterized polyclonal CD8 T cells specific for the...
27.
Georgiev H, Peng C, Huggins M, Jameson S, Hogquist K
Nat Commun . 2021 Apr; 12(1):2308. PMID: 33863906
Conventional T cells are selected by peptide-MHC expressed by cortical epithelial cells in the thymus, and not by cortical thymocytes themselves that do not express MHC I or MHC II....
28.
Jarjour N, Masopust D, Jameson S
Immunity . 2021 Jan; 54(1):14-18. PMID: 33406391
As the SARS-CoV-2 pandemic has progressed, increasing attention has focused on establishing natural and vaccine-induced immunity against this coronavirus and the disease, COVID-19, that it causes. In this Primer, we...
29.
Jameson S
Cold Spring Harb Perspect Biol . 2020 Nov; 13(1). PMID: 33229439
With ever-improving methods of cell characterization, the field of immunology has enjoyed unprecedented opportunities to resolve distinctions between lymphocyte populations. However, this has led to a proliferation of "subset" designations...
30.
Borges da Silva H, Peng C, Wang H, Wanhainen K, Ma C, Lopez S, et al.
Immunity . 2020 Jul; 53(1):158-171.e6. PMID: 32640257
Tissue-resident memory (Trm) CD8 T cells mediate protective immunity in barrier tissues, but the cues promoting Trm cell generation are poorly understood. Sensing of extracellular adenosine triphosphate (eATP) by the...