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Changwei Peng

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Articles 17
Citations 453
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Recent Articles
1.
Jarjour N, Dalzell T, Maurice N, Wanhainen K, Peng C, OFlanagan S, et al.
Immunity . 2025 Mar; 58(3):616-631.e5. PMID: 40023156
Interleukin-7 (IL-7) is considered a critical regulator of memory CD8 T cell homeostasis. However, this is primarily based on circulating memory populations, and the cell-intrinsic requirement for IL-7 signaling during...
2.
Vardam-Kaur T, Banuelos A, Gabaldon-Parish M, Macedo B, Salgado C, Wanhainen K, et al.
iScience . 2024 Jul; 27(7):110290. PMID: 39045105
Sensing of extracellular ATP (eATP) controls CD8 T cell function. Their accumulation can occur through export by specialized molecules, such as the release channel Pannexin 1 (Panx1). Whether Panx1 controls...
3.
Lucas E, Huggins M, Peng C, OConnor C, Gress A, Thefaine C, et al.
Sci Immunol . 2024 Jun; 9(96):eadj8356. PMID: 38941479
KLRG1 CD8 T cells persist for months after clearance of acute infections and maintain high levels of effector molecules, contributing protective immunity against systemic pathogens. Upon secondary infection, these long-lived...
4.
Jarjour N, Dalzell T, Maurice N, Wanhainen K, Peng C, DePauw T, et al.
bioRxiv . 2024 Jun; PMID: 38895229
Interleukin-7 (IL-7) is considered a critical regulator of memory CD8 T cell homeostasis, but this is primarily based on analysis of circulating and not tissue-resident memory (T) subsets. Furthermore, the...
5.
Vardam-Kaur T, Banuelos A, Gabaldon-Parish M, Macedo B, Salgado C, Wanhainen K, et al.
bioRxiv . 2023 May; PMID: 37131831
Sensing of extracellular ATP (eATP) controls CD8 T cell function. Their accumulation can occur through export by specialized molecules, such as the release channel Pannexin-1 (Panx1). Whether Panx1 controls CD8...
6.
Cui R, Peng C, Nie G, Sang S, Ren H, Li W
Front Chem . 2023 Mar; 11:1093435. PMID: 36874070
In view of the composition characteristics of lithium, calcium and bromine rich in Nanyishan oil and gas field brine of western Qaidam Basin, Qinghai Province, as well as based on...
7.
Jarjour N, Wanhainen K, Peng C, Gavil N, Maurice N, Borges da Silva H, et al.
Proc Natl Acad Sci U S A . 2022 Oct; 119(43):e2209021119. PMID: 36260745
Interleukin-15 (IL-15) is often considered a central regulator of memory CD8 T cells, based primarily on studies of recirculating subsets. However, recent work identified IL-15-independent CD8 T cell memory populations,...
8.
Wanhainen K, Peng C, Zhou M, Macedo B, OFlanagan S, Yang T, et al.
Cancer Immunol Res . 2022 May; 10(7):871-884. PMID: 35588154
Expression of the purinergic receptor P2RX7 by CD8+ T cells promotes the generation of memory populations following acute infections. However, data suggest that P2RX7 may limit the efficacy of antitumor...
9.
Vardam-Kaur T, van Dijk S, Peng C, Wanhainen K, Jameson S, Borges da Silva H
J Immunol . 2022 Mar; 208(7):1686-1699. PMID: 35264459
Development of CD8 central memory T (Tcm) and resident memory T (Trm) cells, which promote immunity in the circulation and in barrier tissues, respectively, is not completely understood. Tcm and...
10.
Peng C, Huggins M, Wanhainen K, Knutson T, Lu H, Georgiev H, et al.
Immunity . 2021 Dec; 55(1):98-114.e5. PMID: 34932944
Elevated gene expression of the costimulatory receptor Icos is a hallmark of CD8 tissue-resident memory (Trm) T cells. Here, we examined the contribution of ICOS in Trm cell differentiation. Upon...