Stephanie D Himpsl
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Explore the profile of Stephanie D Himpsl including associated specialties, affiliations and a list of published articles.
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29
Citations
1073
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Recent Articles
1.
Anderson M, Himpsl S, Kingsley L, Smith S, Bachman M, Mobley H
bioRxiv
. 2024 Sep;
PMID: 39229111
is a healthcare-associated pathogen that can cause severe infections including bacteremia and pneumonia. The capsule polysaccharide of is a bacteremia fitness determinant and previous work defined capsule locus (KL) diversity...
2.
Mobley H, Anderson M, Moricz B, Severin G, Holmes C, Ottosen E, et al.
PLoS Pathog
. 2024 Aug;
20(8):e1012495.
PMID: 39178317
There is a critical gap in knowledge about how Gram-negative bacterial pathogens, using survival strategies developed for other niches, cause lethal bacteremia. Facultative anaerobic species of the Enterobacterales order are...
3.
Anderson M, Himpsl S, Mitchell L, Kingsley L, Snider E, Mobley H
PLoS Pathog
. 2022 Mar;
18(3):e1010423.
PMID: 35353877
Serratia marcescens is a versatile opportunistic pathogen that can cause a variety of infections, including bacteremia. Our previous work established that the capsule polysaccharide (CPS) biosynthesis and translocation locus contributes...
4.
Shea A, Stocki J, Himpsl S, Smith S, Mobley H
Infect Immun
. 2021 Dec;
90(2):e0027521.
PMID: 34871042
Uropathogenic Escherichia coli (UPEC) causes the majority of uncomplicated urinary tract infections (UTI), which affect nearly half of women worldwide. Many UPEC strains carry an annotated intimin-like adhesin () locus...
5.
Shea A, Marzoa J, Himpsl S, Smith S, Zhao L, Tran L, et al.
Appl Environ Microbiol
. 2020 May;
86(13).
PMID: 32358013
Urinary tract infections (UTI), the second most diagnosed infectious disease worldwide, are caused primarily by uropathogenic (UPEC), placing a significant financial burden on the health care system. High-throughput transposon mutagenesis...
6.
Forsyth V, Himpsl S, Smith S, Sarkissian C, Mike L, Stocki J, et al.
mBio
. 2020 Apr;
11(2).
PMID: 32345645
Urinary tract infections (UTI) affect half of all women at least once during their lifetime. The rise in the numbers of extended-spectrum beta-lactamase-producing strains and the potential for carbapenem resistance...
7.
Himpsl S, Shea A, Zora J, Stocki J, Foreman D, Alteri C, et al.
PLoS Pathog
. 2020 Feb;
16(2):e1008382.
PMID: 32106241
The energy required for a bacterium to grow and colonize the host is generated by metabolic and respiratory functions of the cell. Proton motive force, produced by these processes, drives...
8.
Kitamoto S, Alteri C, Rodrigues M, Nagao-Kitamoto H, Sugihara K, Himpsl S, et al.
Nat Microbiol
. 2019 Nov;
5(1):116-125.
PMID: 31686025
Metabolic reprogramming is associated with the adaptation of host cells to the disease environment, such as inflammation and cancer. However, little is known about microbial metabolic reprogramming or the role...
9.
Smith S, Himpsl S, Mobley H
Methods Mol Biol
. 2019 Jul;
2021:201-215.
PMID: 31309507
Proteus mirabilis is a major cause of complicated urinary tract infections (UTIs). P. mirabilis' urease activity hydrolyzes urea and raises urine pH levels, which can catalyze bladder and kidney stone...
10.
Himpsl S, Pearson M, Mobley H
Methods Mol Biol
. 2019 Jul;
2021:109-120.
PMID: 31309500
A critical first step in bacterial virulence and colonization is adherence to mucosal surfaces, often mediated by fimbriae and other protein adhesins. Here are described three short methods for studying...