Michael A Bachman
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Explore the profile of Michael A Bachman including associated specialties, affiliations and a list of published articles.
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49
Citations
2122
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Recent Articles
1.
Holmes C, Dailey K, Hullahalli K, Wilcox A, Mason S, Moricz B, et al.
Nat Commun
. 2025 Jan;
16(1):785.
PMID: 39824859
Bacteremia, a leading cause of death, generally arises after bacteria establish infection in a particular tissue and transit to secondary sites. Studying dissemination from primary sites by solely measuring bacterial...
2.
Ring B, Shepard G, Khadka S, Holmes C, Bachman M, Mike L
bioRxiv
. 2024 Nov;
PMID: 39605402
Hypervirulent is associated with severe community-acquired infections. Hypervirulent colonies typically exhibit a mucoid phenotype. mucoidy is influenced by a complex combination of environmental factors and genetic mechanisms. Mucoidy results from...
3.
Holmes C, Albin O, Mobley H, Bachman M
Nat Rev Microbiol
. 2024 Oct;
PMID: 39420097
Bloodstream infections (BSIs) are common in hospitals, often life-threatening and increasing in prevalence. Microorganisms in the blood are usually rapidly cleared by the immune system and filtering organs but, in...
4.
Anderson M, Himpsl S, Kingsley L, Smith S, Bachman M, Mobley H
bioRxiv
. 2024 Sep;
PMID: 39229111
is a healthcare-associated pathogen that can cause severe infections including bacteremia and pneumonia. The capsule polysaccharide of is a bacteremia fitness determinant and previous work defined capsule locus (KL) diversity...
5.
Mobley H, Anderson M, Moricz B, Severin G, Holmes C, Ottosen E, et al.
PLoS Pathog
. 2024 Aug;
20(8):e1012495.
PMID: 39178317
There is a critical gap in knowledge about how Gram-negative bacterial pathogens, using survival strategies developed for other niches, cause lethal bacteremia. Facultative anaerobic species of the Enterobacterales order are...
6.
Vornhagen J, Rao K, Bachman M
mSystems
. 2024 Jul;
9(8):e0078624.
PMID: 38975759
The primary risk factor for infection with members of the species complex is prior gut colonization, and infection is often caused by the colonizing strain. Despite the importance of the...
7.
Brown A, Anderson M, Smith S, Bachman M, Mobley H
mBio
. 2023 Sep;
14(5):e0144823.
PMID: 37681955
Infections of the bloodstream are life-threatening and can result in sepsis. Gram-negative bacteria cause a significant portion of bloodstream infections, which is also referred to as bacteremia. The long-term goal...
8.
Holmes C, Wilcox A, Forsyth V, Smith S, Moricz B, Unverdorben L, et al.
PLoS Pathog
. 2023 Jul;
19(7):e1011233.
PMID: 37463183
Gram-negative bacteremia is a major cause of global morbidity involving three phases of pathogenesis: initial site infection, dissemination, and survival in the blood and filtering organs. Klebsiella pneumoniae is a...
9.
Vornhagen J, Rao K, Bachman M
medRxiv
. 2023 May;
PMID: 37131824
Importance: Colonization is generally the first step in pathogenesis for bacteria with pathogenic potential. This step provides a unique window for intervention since a given potential pathogen has yet to...
10.
Mason S, Vornhagen J, Smith S, Mike L, Mobley H, Bachman M
Infect Immun
. 2023 Jan;
91(2):e0055922.
PMID: 36651775
Healthcare-acquired infections are a leading cause of disease in patients that are hospitalized or in long-term-care facilities. Klebsiella pneumoniae (Kp) is a leading cause of bacteremia, pneumonia, and urinary tract...