Melanie M Pearson
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Explore the profile of Melanie M Pearson including associated specialties, affiliations and a list of published articles.
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32
Citations
954
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Recent Articles
1.
Fitzgerald M, Scavone A, Moolaveesala C, Pearson M, Mobley H
Appl Environ Microbiol
. 2024 Oct;
90(11):e0127324.
PMID: 39475285
Catheter-associated urinary tract infections (CAUTIs) are a significant burden on healthcare systems, accounting for up to 40% of hospital-acquired infections globally. A prevalent CAUTI pathogen, is an understudied Gram-negative bacterium....
2.
Fitzgerald M, Pearson M, Mobley H
J Bacteriol
. 2024 Mar;
206(4):e0003124.
PMID: 38534115
Importance: Catheter-associated urinary tract infections (CAUTIs) account for over 40% of acute nosocomial infections in the USA and generate $340 million in healthcare costs annually. A major causative agent of...
3.
Pearson M, Shea A, Pahil S, Smith S, Forsyth V, Mobley H
Infect Immun
. 2023 Oct;
91(11):e0035523.
PMID: 37850748
Animal models for host-microbial interactions have proven valuable, yielding physiologically relevant data that may be otherwise difficult to obtain. Unfortunately, such models are lacking or nonexistent for many microbes. Here,...
4.
Pearson M, Shea A, Pahil S, Smith S, Forsyth V, Mobley H
Res Sq
. 2023 Jun;
PMID: 37293055
Animal models for host-microbial interactions have proven valuable, yielding physiologically relevant data that may be otherwise difficult to obtain. Unfortunately, such models are lacking or nonexistent for many microbes. Here,...
5.
Pearson M, Pahil S, Forsyth V, Shea A, Mobley H
Microbiol Spectr
. 2022 Nov;
10(6):e0314222.
PMID: 36377916
Ordered transposon libraries are a valuable resource for many bacterial species, especially those with difficult methods for generating targeted genetic mutations. Here, we present the construction of an ordered transposon...
6.
Jiang W, Ubhayasekera W, Breed M, Norsworthy A, Serr N, Mobley H, et al.
PLoS Pathog
. 2020 Aug;
16(8):e1008707.
PMID: 32780778
Proteus mirabilis, a Gram-negative uropathogen, is a major causative agent in catheter-associated urinary tract infections (CAUTI). Mannose-resistant Proteus-like fimbriae (MR/P) are crucially important for P. mirabilis infectivity and are required...
7.
Pearson M
Methods Mol Biol
. 2019 Jul;
2021:121-127.
PMID: 31309501
Mannose-resistant Proteus-like (MR/P) fimbriae, produced by the uropathogen Proteus mirabilis, are major contributors to urinary tract infection. Expression of mrp genes is controlled by an invertible element in the mrp...
8.
Himpsl S, Pearson M, Mobley H
Methods Mol Biol
. 2019 Jul;
2021:109-120.
PMID: 31309500
A critical first step in bacterial virulence and colonization is adherence to mucosal surfaces, often mediated by fimbriae and other protein adhesins. Here are described three short methods for studying...
9.
Pearson M, Himpsl S, Mobley H
Methods Mol Biol
. 2019 Jul;
2021:61-76.
PMID: 31309496
Genetic mutation enables the study of the function of specific genes, particularly when a mutant is compared against its isogenic parent. In Proteus mirabilis bacteria, traditional allelic exchange mutation is...
10.
Pearson M
Methods Mol Biol
. 2019 Jul;
2021:15-25.
PMID: 31309492
Proteus mirabilis is well known for using its flagella to swim through liquids or swarm across solid surfaces. Both phenomena are easy to observe. Described here are two agar-based assays...