Stephanie Borlase
Overview
Explore the profile of Stephanie Borlase including associated specialties, affiliations and a list of published articles.
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5
Citations
64
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Recent Articles
1.
Saulnier O, Zagozewski J, Liang L, Hendrikse L, Layug P, Gordon V, et al.
Nat Cell Biol
. 2024 Jul;
26(8):1233-1246.
PMID: 39025928
OTX2 is a transcription factor and known driver in medulloblastoma (MB), where it is amplified in a subset of tumours and overexpressed in most cases of group 3 and group...
2.
Borlase S, DeCarlo A, Coudiere-Morrison L, Liang L, Porter C, Ramaswamy V, et al.
Cell Death Discov
. 2023 Sep;
9(1):347.
PMID: 37726268
Sonic Hedgehog (SHH) medulloblastomas (MBs) exhibit an intermediate prognosis and extensive intertumoral heterogeneity. While SHH pathway antagonists are effective in post-pubertal patients, younger patients exhibit significant side effects, and tumors...
3.
Hendrikse L, Haldipur P, Saulnier O, Millman J, Sjoboen A, Erickson A, et al.
Nature
. 2022 Nov;
612(7940):E12.
PMID: 36446943
No abstract available.
4.
Hendrikse L, Haldipur P, Saulnier O, Millman J, Sjoboen A, Erickson A, et al.
Nature
. 2022 Sep;
609(7929):1021-1028.
PMID: 36131014
Medulloblastoma (MB) comprises a group of heterogeneous paediatric embryonal neoplasms of the hindbrain with strong links to early development of the hindbrain. Mutations that activate Sonic hedgehog signalling lead to...
5.
Zagozewski J, Borlase S, Guppy B, Coudiere-Morrison L, Shahriary G, Gordon V, et al.
Commun Biol
. 2022 Jul;
5(1):697.
PMID: 35835937
Medulloblastoma (MB) is the most common primary malignant pediatric brain cancer. We recently identified novel roles for the MEK/MAPK pathway in regulating human Sonic Hedgehog (SHH) MB tumorigenesis. The MEK...