Olivier Saulnier
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Explore the profile of Olivier Saulnier including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
529
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Recent Articles
1.
Tiwari A, Paithane U, Friedlein J, Tashiro K, Saulnier O, Barbosa K, et al.
bioRxiv
. 2025 Mar;
PMID: 40027648
MYC-driven (MYC+) cancers are aggressive and often fatal. MYC dysregulation is a key event in these cancers, but overexpression of MYC alone is not always enough to cause cancer. (),...
2.
Li J, Liu H, Wang Z, Zhang J, Chen X, Daniels C, et al.
Neuro Oncol
. 2025 Feb;
PMID: 39957311
Background: Despite numerous studies on medulloblastoma (MB) cell heterogeneity, the spatial characteristics of cellular states remain unclear. Methods: We analyze single-nucleus and spatial transcriptomes and chromatin accessibility from human MB...
3.
Liu H, Zhang J, Wang Z, Wang W, Han D, Chen X, et al.
Cell Rep Med
. 2025 Jan;
6(1):101914.
PMID: 39809264
Medulloblastoma (MB), a heterogeneous pediatric brain tumor, poses challenges in the treatment of tumor recurrence and dissemination. To characterize cellular diversity and genetic features, we comprehensively analyzed single-cell/nucleus RNA sequencing...
4.
Joshi K, Yuan M, Katsushima K, Saulnier O, Ray A, Amankwah E, et al.
Res Sq
. 2024 Sep;
PMID: 39281885
Medulloblastoma, the most common malignant pediatric brain tumor, is classified into four main molecular subgroups, but group 3 and group 4 tumors are difficult to subclassify and have a poor...
5.
Canadas I, Casirati G, Houlahan K, Maxwell K, Mehta A, Parolia A, et al.
Cancer Discov
. 2024 Sep;
14(9):1584-1589.
PMID: 39228299
No abstract available.
6.
Joshi K, Yuan M, Katsushima K, Saulnier O, Ray A, Amankwah E, et al.
Acta Neuropathol Commun
. 2024 Aug;
12(1):138.
PMID: 39198884
Medulloblastoma, the most common malignant pediatric brain tumor, is classified into four main molecular subgroups, but group 3 and group 4 tumors are difficult to subclassify and have a poor...
7.
Butts J, Wu S, Durham M, Dhindsa R, Revelli J, Ljungberg M, et al.
Dev Cell
. 2024 Aug;
59(16):2171-2188.e7.
PMID: 39106860
Proneural transcription factors establish molecular cascades to orchestrate neuronal diversity. One such transcription factor, Atonal homolog 1 (Atoh1), gives rise to cerebellar excitatory neurons and over 30 distinct nuclei in...
8.
Saulnier O, Zagozewski J, Liang L, Hendrikse L, Layug P, Gordon V, et al.
Nat Cell Biol
. 2024 Jul;
26(8):1233-1246.
PMID: 39025928
OTX2 is a transcription factor and known driver in medulloblastoma (MB), where it is amplified in a subset of tumours and overexpressed in most cases of group 3 and group...
9.
Visvanathan A, Saulnier O, Chen C, Haldipur P, Orisme W, Delaidelli A, et al.
Cell
. 2024 Jul;
187(17):4733-4750.e26.
PMID: 38971152
We identify a population of Protogenin-positive (PRTG) MYC NESTIN stem cells in the four-week-old human embryonic hindbrain that subsequently localizes to the ventricular zone of the rhombic lip (RL). Oncogenic...
10.
Katsushima K, Joshi K, Yuan M, Romero B, Batish M, Stapleton S, et al.
Cell Rep
. 2024 Mar;
43(3):113938.
PMID: 38460130
Recent studies suggest that long non-coding RNAs (lncRNAs) contribute to medulloblastoma (MB) formation and progression. We have identified an lncRNA, lnc-HLX-2-7, as a potential therapeutic target in group 3 (G3)...