Tamra E Werbowetski-Ogilvie
Overview
Explore the profile of Tamra E Werbowetski-Ogilvie including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
22
Citations
415
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Martell E, Kuzmychova H, Senthil H, Chawla U, Kaul E, Grewal A, et al.
Neuro Oncol
. 2025 Jan;
PMID: 39798085
Background: The mitochondrial pyruvate carrier (MPC), a central metabolic conduit linking glycolysis and mitochondrial metabolism, is instrumental in energy production. However, the role of the MPC in cancer is controversial....
2.
Saulnier O, Zagozewski J, Liang L, Hendrikse L, Layug P, Gordon V, et al.
Nat Cell Biol
. 2024 Jul;
26(8):1233-1246.
PMID: 39025928
OTX2 is a transcription factor and known driver in medulloblastoma (MB), where it is amplified in a subset of tumours and overexpressed in most cases of group 3 and group...
3.
Borlase S, DeCarlo A, Coudiere-Morrison L, Liang L, Porter C, Ramaswamy V, et al.
Cell Death Discov
. 2023 Sep;
9(1):347.
PMID: 37726268
Sonic Hedgehog (SHH) medulloblastomas (MBs) exhibit an intermediate prognosis and extensive intertumoral heterogeneity. While SHH pathway antagonists are effective in post-pubertal patients, younger patients exhibit significant side effects, and tumors...
4.
Martell E, Kuzmychova H, Kaul E, Senthil H, Chowdhury S, Morrison L, et al.
Nat Commun
. 2023 May;
14(1):2502.
PMID: 37130865
Group 3 medulloblastoma (G3 MB) carries the worst prognosis of all MB subgroups. MYC oncoprotein is elevated in G3 MB tumors; however, the mechanisms that support MYC abundance remain unclear....
5.
Hendrikse L, Haldipur P, Saulnier O, Millman J, Sjoboen A, Erickson A, et al.
Nature
. 2022 Nov;
612(7940):E12.
PMID: 36446943
No abstract available.
6.
Hendrikse L, Haldipur P, Saulnier O, Millman J, Sjoboen A, Erickson A, et al.
Nature
. 2022 Sep;
609(7929):1021-1028.
PMID: 36131014
Medulloblastoma (MB) comprises a group of heterogeneous paediatric embryonal neoplasms of the hindbrain with strong links to early development of the hindbrain. Mutations that activate Sonic hedgehog signalling lead to...
7.
Zagozewski J, Borlase S, Guppy B, Coudiere-Morrison L, Shahriary G, Gordon V, et al.
Commun Biol
. 2022 Jul;
5(1):697.
PMID: 35835937
Medulloblastoma (MB) is the most common primary malignant pediatric brain cancer. We recently identified novel roles for the MEK/MAPK pathway in regulating human Sonic Hedgehog (SHH) MB tumorigenesis. The MEK...
8.
Chukwueke U, Vera E, Acquaye A, Hervey-Jumper S, Odia Y, Klesse L, et al.
Neuro Oncol
. 2021 Jul;
23(11):1845-1858.
PMID: 34302487
Background: Neuro-oncology has grown tremendously since 2010, marked by increasing society membership, specialized clinical expertise, and new journals. Yet, modest improvement in racial/ethnic diversity amongst clinical trial participants, researchers, and...
9.
Werbowetski-Ogilvie T
FEBS J
. 2021 Mar;
289(7):1765-1778.
PMID: 33714236
The cancer stem cell (CSC) model posits that tumors contain subpopulations that display defining features of normal stem cells including self-renewal capacity and differentiation. Tumor cells exhibiting these features are...
10.
Zagozewski J, Shahriary G, Morrison L, Saulnier O, Stromecki M, Fresnoza A, et al.
Nat Commun
. 2020 Jul;
11(1):3627.
PMID: 32686664
OTX2 is a potent oncogene that promotes tumor growth in Group 3 medulloblastoma. However, the mechanisms by which OTX2 represses neural differentiation are not well characterized. Here, we perform extensive...