Steinar M Paulsen
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Explore the profile of Steinar M Paulsen including associated specialties, affiliations and a list of published articles.
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11
Citations
121
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Recent Articles
1.
Arnesen H, Haj-Yasein N, Tungen J, Soedling H, Matthews J, Paulsen S, et al.
Bioorg Med Chem
. 2019 Jul;
27(18):4059-4068.
PMID: 31351846
The peroxisome proliferator activated receptors (PPARs) are important drug targets in treatment of metabolic and inflammatory disorders. Fibrates, acting as PPARα agonists, have been widely used lipid-lowering agents for decades....
2.
Saether T, Paulsen S, Tungen J, Vik A, Aursnes M, Holen T, et al.
Eur J Med Chem
. 2018 Jun;
155:736-753.
PMID: 29940464
Obesity and associated disorders such as metabolic syndrome and type 2 diabetes (T2D) have reached epidemic proportions. Several natural products have been reported as Peroxisome Proliferator-Activated Receptor (PPAR) agonists, functioning...
3.
Moldes-Anaya A, Saether T, Uhlig S, Nebb H, Larsen T, Eilertsen H, et al.
Mar Drugs
. 2017 Jun;
15(6).
PMID: 28587091
The peroxisome proliferator-activated receptors (PPARs) function as ligand-activated transcription factors that convert signals in the form of lipids to physiological responses through the activation of metabolic target genes. Due to...
4.
Scotti J, Leung I, Ge W, Bentley M, Paps J, Kramer H, et al.
Proc Natl Acad Sci U S A
. 2014 Sep;
111(37):13331-6.
PMID: 25197067
The roles of 2-oxoglutarate (2OG)-dependent prolyl-hydroxylases in eukaryotes include collagen stabilization, hypoxia sensing, and translational regulation. The hypoxia-inducible factor (HIF) sensing system is conserved in animals, but not in other...
5.
Ahmad R, Hansen G, Hansen H, Hjerde E, Pedersen H, Paulsen S, et al.
J Mol Microbiol Biotechnol
. 2013 Jan;
22(6):352-60.
PMID: 23295256
Bacterial small RNAs (sRNAs) are trans-encoded regulatory RNAs that typically bind mRNAs by short-sequence complementarities and change the expression of the corresponding proteins. Some of the well-characterized sRNAs serve critical...
6.
Pedersen H, Hjerde E, Paulsen S, Hansen H, Olsen L, Thode S, et al.
Mar Genomics
. 2011 Jul;
3(3-4):193-200.
PMID: 21798213
Aliivibrio salmonicida causes "cold-water vibriosis" (or "Hitra disease") in fish, including marine-reared Atlantic salmon. During development of the disease the bacterium will encounter macrophages with antibacterial activities such as production...
7.
Karlsen C, Espelid S, Willassen N, Paulsen S
Dis Aquat Organ
. 2011 Apr;
93(3):215-23.
PMID: 21516974
Aliivibrio salmonicida is the aetiological agent of cold water vibriosis affecting farmed fish species, a disease that today is fully controlled by vaccination. However, the molecular mechanisms behind the successful...
8.
Karlsen C, Paulsen S, Tunsjo H, Krinner S, Sorum H, Haugen P, et al.
Microb Pathog
. 2008 Jul;
45(4):258-64.
PMID: 18634865
The success of several Vibrio species, including Vibrio cholerae, Vibrio anguillarum and Vibrio fischeri in colonizing their symbiont, or causing infection is linked to flagella-based motility. It is during early...
9.
Raeder I, Paulsen S, Smalas A, Willassen N
Microb Pathog
. 2006 Dec;
42(1):36-45.
PMID: 17145162
Vibrio salmonicida is the causative agent of cold-water vibriosis in farmed marine fish species. Adherence of pathogenic bacteria to mucosal surfaces is considered to be the first steps in the...
10.
Niiranen L, Espelid S, Karlsen C, Mustonen M, Paulsen S, Heikinheimo P, et al.
Protein Expr Purif
. 2006 Oct;
52(1):210-8.
PMID: 17064934
Functional and structural studies require gene overexpression and purification of soluble proteins. We wanted to express proteins from the psychrophilic bacterium Vibrio salmonicida in Escherichia coli, but encountered solubility problems....