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Stefan Stevanovic

Explore the profile of Stefan Stevanovic including associated specialties, affiliations and a list of published articles. Areas
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Articles 237
Citations 7384
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Recent Articles
1.
Yarmarkovich M, Marshall Q, Warrington J, Premaratne R, Farrel A, Groff D, et al.
Nature . 2023 Nov; 623(7988):872. PMID: 37938785
No abstract available.
2.
Yarmarkovich M, Marshall Q, Warrington J, Premaratne R, Farrel A, Groff D, et al.
Nature . 2023 Nov; 623(7988):820-827. PMID: 37938771
The majority of oncogenic drivers are intracellular proteins, constraining their immunotherapeutic targeting to mutated peptides (neoantigens) presented by individual human leukocyte antigen (HLA) allotypes. However, most cancers have a modest...
3.
Sarango G, Richetta C, Pereira M, Kumari A, Ghosh M, Bertrand L, et al.
EMBO Rep . 2022 Oct; 23(12):e55470. PMID: 36215666
CD4 T lymphocytes play a major role in the establishment and maintenance of immunity. They are activated by antigenic peptides derived from extracellular or newly synthesized (endogenous) proteins presented by...
4.
Yarmarkovich M, Marshall Q, Warrington J, Premaratne R, Farrel A, Groff D, et al.
Nature . 2021 Nov; 599(7885):477-484. PMID: 34732890
The majority of oncogenic drivers are intracellular proteins, thus constraining their immunotherapeutic targeting to mutated peptides (neoantigens) presented by individual human leukocyte antigen (HLA) allotypes. However, most cancers have a...
5.
Bittner Z, Liu X, Mateo Tortola M, Tapia-Abellan A, Shankar S, Andreeva L, et al.
J Exp Med . 2021 Sep; 218(11). PMID: 34554188
Activity of the NLRP3 inflammasome, a critical mediator of inflammation, is controlled by accessory proteins, posttranslational modifications, cellular localization, and oligomerization. How these factors relate is unclear. We show that...
6.
Hottler A, Marz L, Lubke M, Rammensee H, Stevanovic S
Front Immunol . 2021 Jul; 12:700438. PMID: 34322126
Reactivation of Human Cytomegalovirus (HCMV) and Human Adenovirus (HAdV) in immunocompromised patients following stem cell transplantation (SCT) or solid organ transplantation (SOT) is associated with high morbidity and mortality. The...
7.
Halabi S, Ghosh M, Stevanovic S, Rammensee H, Bertzbach L, Kaufer B, et al.
PLoS Biol . 2021 Apr; 19(4):e3001057. PMID: 33901176
Viral diseases pose major threats to humans and other animals, including the billions of chickens that are an important food source as well as a public health concern due to...
8.
Marcu A, Bichmann L, Kuchenbecker L, Kowalewski D, Freudenmann L, Backert L, et al.
J Immunother Cancer . 2021 Apr; 9(4). PMID: 33858848
Background: The human leucocyte antigen (HLA) complex controls adaptive immunity by presenting defined fractions of the intracellular and extracellular protein content to immune cells. Understanding the benign HLA ligand repertoire...
9.
Schollhorn A, Schuhmacher J, Besedovsky L, Fendel R, Jensen A, Stevanovic S, et al.
Front Immunol . 2021 Apr; 12:626308. PMID: 33854501
We have previously shown that conformational change in the β-integrin is a very early activation marker that can be detected with fluorescent multimers of its ligand intercellular adhesion molecule (ICAM)-1...
10.
Platten M, Bunse L, Wick A, Bunse T, Le Cornet L, Harting I, et al.
Nature . 2021 Mar; 592(7854):463-468. PMID: 33762734
Mutated isocitrate dehydrogenase 1 (IDH1) defines a molecularly distinct subtype of diffuse glioma. The most common IDH1 mutation in gliomas affects codon 132 and encodes IDH1(R132H), which harbours a shared...