Stefan H Oehlers
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Explore the profile of Stefan H Oehlers including associated specialties, affiliations and a list of published articles.
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52
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1193
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Recent Articles
1.
Wright K, Han D, Song R, de Silva K, Plain K, Purdie A, et al.
Life Sci Alliance
. 2024 Feb;
7(4).
PMID: 38307625
Regulation of host miRNA expression is a contested node that controls the host immune response to mycobacterial infection. The host must counter subversive efforts of pathogenic mycobacteria to launch a...
2.
Johansen M, Spaink H, Oehlers S, Kremer L
Trends Microbiol
. 2023 Dec;
32(7):663-677.
PMID: 38135617
The incidence of infections due to nontuberculous mycobacteria (NTM) has increased rapidly in recent years, surpassing tuberculosis in developed countries. Due to inherent antimicrobial resistance, NTM infections are particularly difficult...
3.
Resseguier J, Nguyen-Chi M, Wohlmann J, Rigaudeau D, Salinas I, Oehlers S, et al.
Sci Adv
. 2023 Nov;
9(44):eadj0101.
PMID: 37910624
The constant exposure of the fish branchial cavity to aquatic pathogens causes local mucosal immune responses to be extremely important for their survival. Here, we used a marker for T...
4.
Shihana F, Manuneedhi Cholan P, Fraser S, Oehlers S, Seth D
Liver Int
. 2023 Aug;
43(11):2455-2468.
PMID: 37650211
Background: Accumulation of lipid in the liver is the first hallmark of both alcohol-related liver disease (ALD) and non-alcohol-related fatty liver disease (NAFLD). Recent studies indicate that specific mutations in...
5.
Dupuy A, Aponte-Santamaria C, Yeheskel A, Hortle E, Oehlers S, Grater F, et al.
Circ Res
. 2023 Apr;
132(9):e151-e168.
PMID: 37021588
Background: Neutrophil migration is critical to the initiation and resolution of inflammation. Macrophage-1 antigen (Mac-1; CD11b/CD18, αMβ2) is a leukocyte integrin essential for firm adhesion to endothelial ICAM-1 (intercellular adhesion...
6.
Kam J, Wright K, Britton W, Oehlers S
Microb Pathog
. 2022 May;
167:105590.
PMID: 35588967
Mycobacterium abscessus infections are of increasing global prevalence and are often difficult to treat due to complex antibiotic resistance profiles. While there are similarities between the pathogenesis of M. abscessus...
7.
Hortle E, Tran V, Wright K, Fontaine A, Pinello N, ORourke M, et al.
Life Sci Alliance
. 2022 May;
5(9).
PMID: 35545295
Pathogenic mycobacteria inhibit inflammasome activation to establish infection. Although it is known that potassium efflux is a trigger for inflammasome activation, the interaction between mycobacterial infection, potassium efflux, and inflammasome...
8.
Morris S, Wright K, Malyla V, Britton W, Hansbro P, Manuneedhi Cholan P, et al.
Curr Res Immunol
. 2022 May;
2:229-236.
PMID: 35492390
Cigarette smoke (CS)-induced inflammation leads to a range of diseases including chronic obstructive pulmonary disease and cancer. The gut microbiota is a major modifying environmental factor that determine the severity...
9.
Kam J, Cheng T, Garland D, Britton W, Tobin D, Oehlers S
Pathog Dis
. 2022 Apr;
80(1).
PMID: 35438161
Mycobacterial granuloma formation involves significant stromal remodeling including the growth of leaky, granuloma-associated vasculature. These permeable blood vessels aid mycobacterial growth, as antiangiogenic or vascular normalizing therapies are beneficial host-directed...
10.
Hawkins P, Hoi D, Cheung C, Wang T, Quan D, Sasi V, et al.
J Med Chem
. 2022 Mar;
65(6):4893-4908.
PMID: 35293761
Ohmyungsamycin A and ecumicin are structurally related cyclic depsipeptide natural products that possess activity against (Mtb), the causative agent of tuberculosis (TB). Herein, we describe the design and synthesis of...