Philip S Crosier
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Explore the profile of Philip S Crosier including associated specialties, affiliations and a list of published articles.
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60
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2138
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Recent Articles
1.
Darroch H, Keerthisinghe P, Sung Y, Rolland L, Prankerd-Gough A, Crosier P, et al.
Sci Adv
. 2023 Sep;
9(36):eadf9904.
PMID: 37672586
Hematopoietic stem and progenitor cells (HSPCs) respond to infection by proliferating and generating in-demand neutrophils through a process called emergency granulopoiesis (EG). Recently, infection-induced changes in HSPCs have also been...
2.
Britto D, He J, Misa J, Chen W, Kakadia P, Grimm L, et al.
Development
. 2022 Oct;
149(21).
PMID: 36205097
Lymphangiogenesis is a dynamic process that involves the directed migration of lymphatic endothelial cells (LECs) to form lymphatic vessels. The molecular mechanisms that underpin lymphatic vessel patterning are not fully...
3.
Okuda K, Ng M, Ruslan N, Bower N, Song D, Chen H, et al.
Pharmaceuticals (Basel)
. 2021 Jul;
14(7).
PMID: 34206901
Lymphangiogenesis, the formation of new lymphatic vessels from pre-existing vasculature, plays critical roles in disease, including in cancer metastasis and chronic inflammation. Preclinical and recent clinical studies have now demonstrated...
4.
Zebrafish facial lymphatics develop through sequential addition of venous and non-venous progenitors
Eng T, Chen W, Okuda K, Misa J, Padberg Y, Crosier K, et al.
EMBO Rep
. 2019 Mar;
20(5).
PMID: 30877134
Lymphatic vessels are known to be derived from veins; however, recent lineage-tracing experiments propose that specific lymphatic networks may originate from both venous and non-venous sources. Despite this, direct evidence...
5.
Wu Z, Koh B, Lawrence L, Kanamala M, Pool B, Svirskis D, et al.
Zebrafish
. 2019 Feb;
16(2):171-181.
PMID: 30724716
Chemical interventions are regularly used to examine and manipulate macrophage function in larval zebrafish. Given chemicals are typically administered by simple immersion or injection, it is not possible to resolve...
6.
Britto D, Wyroba B, Chen W, Lockwood R, Tran K, Shepherd P, et al.
Dis Model Mech
. 2018 Nov;
11(12).
PMID: 30396905
Tumour angiogenesis has long been a focus of anti-cancer therapy; however, anti-angiogenic cancer treatment strategies have had limited clinical success. Tumour-associated myeloid cells are believed to play a role in...
7.
Hall C, Sanderson L, Lawrence L, Pool B, van der Kroef M, Ashimbayeva E, et al.
J Clin Invest
. 2018 Mar;
128(5):1752-1771.
PMID: 29584621
Gout is the most common inflammatory arthritis affecting men. Acute gouty inflammation is triggered by monosodium urate (MSU) crystal deposition in and around joints that activates macrophages into a proinflammatory...
8.
Du L, Darroch H, Keerthisinghe P, Ashimbayeva E, Astin J, Crosier K, et al.
Sci Rep
. 2017 Oct;
7(1):12657.
PMID: 28978916
The circadian clock, which evolved to help organisms harmonize physiological responses to external conditions (such as the light/dark cycle, LD), is emerging as an important regulator of the immune response...
9.
Hasegawa T, Hall C, Crosier P, Abe G, Kawakami K, Kudo A, et al.
Elife
. 2017 Feb;
6.
PMID: 28229859
Cellular responses to injury are crucial for complete tissue regeneration, but their underlying processes remain incompletely elucidated. We have previously reported that myeloid-defective zebrafish mutants display apoptosis of regenerative cells...
10.
Fehr A, Ruetten M, Seth-Smith H, Nufer L, Voegtlin A, Lehner A, et al.
Front Microbiol
. 2016 Dec;
7:1829.
PMID: 27917158
Obligate intracellular chlamydial bacteria of the Planctomycetes-Verrucomicrobia-Chlamydiae (PVC) superphylum are important pathogens of terrestrial and marine vertebrates, yet many features of their pathogenesis and host specificity are still unknown. This...