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Stefan Bonne

Explore the profile of Stefan Bonne including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 967
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Recent Articles
1.
Swales N, Martens G, Bonne S, Heremans Y, Borup R, Van de Casteele M, et al.
PLoS One . 2012 May; 7(5):e37055. PMID: 22606327
Aims/hypothesis: Duct cells isolated from adult human pancreas can be reprogrammed to express islet beta cell genes by adenoviral transduction of the developmental transcription factor neurogenin3 (Ngn3). In this study...
2.
Baeyens L, Bonne S, Bos T, Rooman I, Peleman C, Lahoutte T, et al.
Gastroenterology . 2009 Feb; 136(5):1750-60.e13. PMID: 19208356
Background & Aims: Exocrine acinar cells in the pancreas are highly differentiated cells that retain a remarkable degree of plasticity. After isolation and an initial phase of dedifferentiation in vitro,...
3.
Vandenbroucke R, De Geest B, Bonne S, Vinken M, Van Haecke T, Heimberg H, et al.
J Gene Med . 2008 May; 10(7):783-94. PMID: 18470950
Background: Small interfering (si)RNA mediated inhibition of oncogenes or viral genes may offer great opportunities for the treatment of several diseases such as hepatocellular carcinoma and viral hepatitis. However, the...
4.
Xu X, DHoker J, Stange G, Bonne S, De Leu N, Xiao X, et al.
Cell . 2008 Feb; 132(2):197-207. PMID: 18243096
Novel strategies in diabetes therapy would obviously benefit from the use of beta (beta) cell stem/progenitor cells. However, whether or not adult beta cell progenitors exist is one of the...
5.
Sklyarova T, Bonne S, Dhooge P, Denecker G, Goossens S, De Rycke R, et al.
J Invest Dermatol . 2007 Dec; 128(6):1375-85. PMID: 18079750
We generated mice deficient in plakophilin-3 (PKP3), a member of the Armadillo-repeat family and a component of desmosomes and stress granules in epithelial cells. In these mice, several subsets of...
6.
Goossens S, Janssens B, Bonne S, De Rycke R, Braet F, van Hengel J, et al.
J Cell Sci . 2007 May; 120(Pt 12):2126-36. PMID: 17535849
Alpha-catenins play key functional roles in cadherin-catenin cell-cell adhesion complexes. We previously reported on alphaT-catenin, a novel member of the alpha-catenin protein family. alphaT-catenin is expressed predominantly in cardiomyocytes, where...
7.
Aigner K, Descovich L, Mikula M, Sultan A, Dampier B, Bonne S, et al.
FEBS Lett . 2007 Mar; 581(8):1617-24. PMID: 17391671
Plakophilin 3 (PKP3) belongs to the p120ctn family of armadillo-related proteins predominantly functioning in desmosome formation. Here we report that PKP3 is transcriptionally repressed by the E-cadherin repressor ZEB1 in...
8.
Mellitzer G, Bonne S, Luco R, Van de Casteele M, Lenne-Samuel N, Collombat P, et al.
EMBO J . 2006 Mar; 25(6):1344-52. PMID: 16511571
Neurogenin 3 (Ngn3) is key for endocrine cell specification in the embryonic pancreas and induction of a neuroendocrine cell differentiation program by misexpression in adult pancreatic duct cells. We identify...
9.
Bonne S, Gilbert B, Hatzfeld M, Chen X, Green K, van Roy F
J Cell Biol . 2003 Apr; 161(2):403-16. PMID: 12707304
Plakophilin 3 (PKP3) is a recently described armadillo protein of the desmosomal plaque, which is synthesized in simple and stratified epithelia. We investigated the localization pattern of endogenous and exogenous...
10.
Chen X, Bonne S, Hatzfeld M, van Roy F, Green K
J Biol Chem . 2002 Jan; 277(12):10512-22. PMID: 11790773
Plakophilins are a subfamily of p120-related arm-repeat proteins that can be found in both desmosomes and the nucleus. Among the three known plakophilin members, plakophilin 1 has been linked to...