Mark Van de Casteele
Overview
Explore the profile of Mark Van de Casteele including associated specialties, affiliations and a list of published articles.
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40
Citations
1616
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Recent Articles
1.
Vandewalle J, Desouter A, Van der Auwera B, Tenoutasse S, Gillard P, De Block C, et al.
Clin Exp Immunol
. 2023 Jan;
211(3):224-232.
PMID: 36622793
The HLA region is the major genetic risk determinant of Type 1 diabetes. How non-HLA loci contribute to the genetic risk is incompletely understood, but there are indications that at...
2.
Vandewalle J, Van der Auwera B, Amin H, Quartier E, Desouter A, Tenoutasse S, et al.
Diabetologia
. 2021 Aug;
64(11):2511-2516.
PMID: 34448034
Aims/hypothesis: We examined whether the non-HLA susceptibility locus ERBB3/IKZF4 influences progression of type 1 diabetes stage specifically according to sex. Methods: SNPs of ERBB3 (rs2292239 T/G) and IKZF4 (rs1701704 G/T)...
3.
Baeyens L, Lemper M, Leuckx G, De Groef S, Bonfanti P, Stange G, et al.
Nat Biotechnol
. 2020 Feb;
38(3):374.
PMID: 32066957
This article has been retracted; see accompanying Retraction Note, which can be accessed via a link at the top of the paper.
4.
Sojoodi M, Stradiot L, Tanaka K, Heremans Y, Leuckx G, Besson V, et al.
Diabetologia
. 2016 May;
59(7):1474-1479.
PMID: 27130279
Aims/hypothesis: Pw1 or paternally-expressed gene 3 (Peg3) encodes a zinc finger transcription factor that is widely expressed during mouse embryonic development and later restricted to multiple somatic stem cell lineages...
5.
De Groef S, Staels W, Van Gassen N, Lemper M, Yuchi Y, Sojoodi M, et al.
Diabetologia
. 2016 Apr;
59(9):1834-7.
PMID: 27053238
The generation of beta(-like) cells to compensate for their absolute or relative shortage in type 1 and type 2 diabetes is an obvious therapeutic strategy. Patients first received grafts of...
6.
De Groef S, Leuckx G, Van Gassen N, Staels W, Cai Y, Yuchi Y, et al.
J Vis Exp
. 2015 Aug;
(102):e52765.
PMID: 26273954
Expansion of pancreatic beta cells in vivo or ex vivo, or generation of beta cells by differentiation from an embryonic or adult stem cell, can provide new expandable sources of...
7.
Yuchi Y, Cai Y, Legein B, De Groef S, Leuckx G, Coppens V, et al.
Diabetes
. 2015 May;
64(9):3218-28.
PMID: 26015547
Identifying pathways for β-cell generation is essential for cell therapy in diabetes. We investigated the potential of 17β-estradiol (E2) and estrogen receptor (ER) signaling for stimulating β-cell generation during embryonic...
8.
Van Gassen N, Staels W, Van Overmeire E, De Groef S, Sojoodi M, Heremans Y, et al.
Stem Cells Transl Med
. 2015 Apr;
4(6):555-63.
PMID: 25848123
Unlabelled: Macrophages are classically considered detrimental for pancreatic β-cell survival and function, thereby contributing to β-cell failure in both type 1 (T1D) and 2 (T2D) diabetes mellitus. In addition, adipose...
9.
Van Gassen N, Van Overmeire E, Leuckx G, Heremans Y, De Groef S, Cai Y, et al.
Eur J Immunol
. 2015 Feb;
45(5):1482-93.
PMID: 25645754
Pancreas injury by partial duct ligation (PDL) activates a healing response, encompassing β-cell neogenesis and proliferation. Macrophages (MΦs) were recently shown to promote β-cell proliferation after PDL, but they remain...
10.
Van de Casteele M, Leuckx G, Cai Y, Yuchi Y, Coppens V, De Groef S, et al.
Diabetes
. 2014 Jul;
63(8):2567-77.
PMID: 25060885
No abstract available.