Stacy A Marshall
Overview
Explore the profile of Stacy A Marshall including associated specialties, affiliations and a list of published articles.
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25
Citations
2622
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0
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Recent Articles
1.
Gonzalez-Buendia E, Zhao J, Wang L, Mukherjee S, Zhang D, Arrieta V, et al.
Clin Cancer Res
. 2021 Aug;
27(20):5669-5680.
PMID: 34433651
Purpose: The epigenetic mechanisms involved in transcriptional regulation leading to malignant phenotype in gliomas remains poorly understood. Topoisomerase IIB (TOP2B), an enzyme that decoils and releases torsional forces in DNA,...
2.
Cao K, Ugarenko M, Ozark P, Wang J, Marshall S, Rendleman E, et al.
Proc Natl Acad Sci U S A
. 2020 Oct;
117(44):27365-27373.
PMID: 33077595
Actively transcribed genes in mammals are decorated by H3K79 methylation, which is correlated with transcription levels and is catalyzed by the histone methyltransferase DOT1L. DOT1L is required for mammalian development,...
3.
Sze C, Ozark P, Cao K, Ugarenko M, Das S, Wang L, et al.
Sci Adv
. 2020 Jul;
6(26):eaaz4764.
PMID: 32637595
Set1A and Set1B, two members of the COMPASS family of methyltransferases that methylate the histone H3 lysine 4 (H3K4) residue, have been accredited as primary depositors of global H3K4 trimethylation...
4.
Douillet D, Sze C, Ryan C, Piunti A, Shah A, Ugarenko M, et al.
Nat Genet
. 2020 May;
52(6):615-625.
PMID: 32393859
The COMPASS protein family catalyzes histone H3 Lys 4 (H3K4) methylation and its members are essential for regulating gene expression. MLL2/COMPASS methylates H3K4 on many developmental genes and bivalent clusters....
5.
Rosencrance C, Ammouri H, Yu Q, Ge T, Rendleman E, Marshall S, et al.
Mol Cell
. 2020 Apr;
78(1):112-126.e12.
PMID: 32243828
Delineating how chromosomes fold at length scales beyond one megabase remains obscure relative to smaller-scale folding into TADs, loops, and nucleosomes. We find that rather than simply unfolding chromatin, histone...
6.
Aoi Y, Smith E, Shah A, Rendleman E, Marshall S, Woodfin A, et al.
Mol Cell
. 2020 Mar;
78(2):261-274.e5.
PMID: 32155413
RNA polymerase II (RNA Pol II) is generally paused at promoter-proximal regions in most metazoans, and based on in vitro studies, this function has been attributed to the negative elongation...
7.
Zhao Z, Wang L, Volk A, Birch N, Stoltz K, Bartom E, et al.
Genes Dev
. 2018 Dec;
33(1-2):61-74.
PMID: 30573454
Chromosomal translocations of the Mixed-lineage leukemia 1 () gene generate MLL chimeras that drive the pathogenesis of acute myeloid and lymphoid leukemia. The untranslocated MLL1 is a substrate for proteolytic...
8.
Reyfman P, Walter J, Joshi N, Anekalla K, McQuattie-Pimentel A, Chiu S, et al.
Am J Respir Crit Care Med
. 2018 Dec;
199(12):1517-1536.
PMID: 30554520
The contributions of diverse cell populations in the human lung to pulmonary fibrosis pathogenesis are poorly understood. Single-cell RNA sequencing can reveal changes within individual cell populations during pulmonary fibrosis...
9.
Wang L, Ozark P, Smith E, Zhao Z, Marshall S, Rendleman E, et al.
Sci Adv
. 2018 Nov;
4(11):eaau6986.
PMID: 30417100
The tet methylcytosine dioxygenase 2 (TET2) enzyme catalyzes the conversion of the modified DNA base 5-methylcytosine to 5-hydroxymethylcytosine. TET2 is frequently mutated or dysregulated in multiple human cancers, and loss...
10.
Liang K, Smith E, Aoi Y, Stoltz K, Katagi H, Woodfin A, et al.
Cell
. 2018 Oct;
175(3):766-779.e17.
PMID: 30340042
The super elongation complex (SEC) is required for robust and productive transcription through release of RNA polymerase II (Pol II) with its P-TEFb module and promoting transcriptional processivity with its...