Staci N Keller
Overview
Explore the profile of Staci N Keller including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
486
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0
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Recent Articles
11.
Maines L, Fitzpatrick L, French K, Zhuang Y, Xia Z, Keller S, et al.
Dig Dis Sci
. 2007 Dec;
53(4):997-1012.
PMID: 18058233
A critical step in the mechanism of action of inflammatory cytokines is the stimulation of sphingolipid metabolism, including activation of sphingosine kinase (SK), which produces the mitogenic and proinflammatory lipid...
12.
Ducker C, Griffel L, Smith R, Keller S, Zhuang Y, Xia Z, et al.
Mol Cancer Ther
. 2006 Aug;
5(7):1647-59.
PMID: 16891450
The covalent attachment of palmitate to specific proteins by the action of palmitoyl acyltransferases (PAT) plays critical roles in the biological activities of several oncoproteins. Two PAT activities are expressed...
13.
French K, Upson J, Keller S, Zhuang Y, Yun J, Smith C
J Pharmacol Exp Ther
. 2006 Apr;
318(2):596-603.
PMID: 16632640
Sphingosine kinase (SK) is an oncogenic sphingolipid-metabolizing enzyme that catalyzes the formation of the mitogenic second messenger sphingosine-1-phosphate (S1P) at the expense of proapoptotic ceramide. Thus, SK is an attractive...