Sree Deepthi Muthukrishnan
Overview
Explore the profile of Sree Deepthi Muthukrishnan including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
312
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Recent Articles
11.
Duhachek-Muggy S, Bhat K, Medina P, Cheng F, He L, Alli C, et al.
Stem Cells Transl Med
. 2019 Aug;
9(1):106-119.
PMID: 31464098
The objective of the study was to identify the mechanism of action for a radiation mitigator of the gastrointestinal (GI) acute radiation syndrome (ARS), identified in an unbiased high-throughput screen....
12.
Muthukrishnan S, Alvarado A, Kornblum H
Cell Stem Cell
. 2018 Apr;
22(4):473-474.
PMID: 29625062
Little is currently known about how cancer stem-like cells (CSCs) interact with their more restricted progeny. In this issue of Cell Stem Cell, Wang et al. (2018) demonstrate a novel...
13.
Muthukrishnan S, Ryzhov S, Karolak M, Oxburgh L
Dis Model Mech
. 2017 Dec;
11(1).
PMID: 29196442
The final nephron number in an adult kidney is regulated by nephron progenitor cell availability and collecting duct branching in the fetal period. Fetal environmental perturbations that cause reductions in...
14.
Oxburgh L, Muthukrishnan S, Brown A
Results Probl Cell Differ
. 2017 Apr;
60:137-164.
PMID: 28409345
New nephrons are induced by the interaction between mesenchymal progenitor cells and collecting duct tips, both of which are located at the outer edge of the kidney. This leading edge...
15.
Muthukrishnan S, Yang X, Friesel R, Oxburgh L
Nat Commun
. 2015 Dec;
6:10027.
PMID: 26634297
Self-renewal of nephron progenitor cells (NPCs) is governed by BMP, FGF and WNT signalling. Mechanisms underlying cross-talk between these pathways at the molecular level are largely unknown. Here we delineate...
16.
Brown A, Muthukrishnan S, Oxburgh L
Dev Cell
. 2015 Jul;
34(2):229-41.
PMID: 26190145
FGF, BMP, and WNT balance embryonic nephron progenitor cell (NPC) renewal and differentiation. By modulating these pathways, we have created an in vitro niche in which NPCs from embryonic kidneys...
17.
Oxburgh L, Brown A, Muthukrishnan S, Fetting J
Pediatr Nephrol
. 2013 Aug;
29(4):531-6.
PMID: 23954916
Bone morphogenetic protein (BMP) signaling plays an essential role in many aspects of kidney development, and is a major determinant of outcome in kidney injury. BMP treatment is also an...
18.
Brown A, Muthukrishnan S, Guay J, Adams D, Schafer D, Fetting J, et al.
Proc Natl Acad Sci U S A
. 2013 Mar;
110(12):4640-5.
PMID: 23487745
Embryonic nephron progenitor cells are segregated in molecularly distinct compartments of unknown function. Our study reveals an integral role for bone morphogenetic protein-SMAD in promoting transition of progenitors from the...