Spyros Petrakis
Overview
Explore the profile of Spyros Petrakis including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
204
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0
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Recent Articles
1.
Vagiona A, Notopoulou S, Zdrahal Z, Goncalves-Kulik M, Petrakis S, Andrade-Navarro M
PLoS One
. 2025 Mar;
20(3):e0319084.
PMID: 40029919
Protein-protein interactions (PPIs) form a complex network called "interactome" that regulates many functions in the cell. In recent years, there is an increasing accumulation of evidence supporting the existence of...
2.
Gkekas I, Katsamakas S, Mylonas S, Fotopoulou T, Magoulas G, Tenchiu A, et al.
J Chem Inf Model
. 2024 Nov;
64(22):8562-8585.
PMID: 39535926
Coronavirus disease 2019 (COVID-19) is caused by a new, highly pathogenic severe-acute-respiratory syndrome coronavirus 2 (SARS-CoV-2) that infects human cells through its transmembrane spike (S) glycoprotein. The receptor-binding domain (RBD)...
3.
Lisowski P, Lickfett S, Rybak-Wolf A, Menacho C, Le S, Pentimalli T, et al.
Nat Commun
. 2024 Aug;
15(1):7027.
PMID: 39174523
Expansion of the glutamine tract (poly-Q) in the protein huntingtin (HTT) causes the neurodegenerative disorder Huntington's disease (HD). Emerging evidence suggests that mutant HTT (mHTT) disrupts brain development. To gain...
4.
Gkekas I, Vagiona A, Pechlivanis N, Kastrinaki G, Pliatsika K, Iben S, et al.
Front Mol Neurosci
. 2023 Dec;
16:1280546.
PMID: 38125008
Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disease caused by a trinucleotide (CAG) repeat expansion in the ATXN1 gene. It is characterized by the presence of polyglutamine...
5.
Pechlivani E, Pemas S, Kanlis A, Pechlivani P, Petrakis S, Papadimitriou A, et al.
Micromachines (Basel)
. 2023 Oct;
14(10).
PMID: 37893266
In the last decade, there has been a notable advancement in diverse bioreactor types catering to various applications. However, conventional bioreactors often exhibit bulkiness and high costs, making them less...
6.
Kastrinaki G, Pechlivani E, Gkekas I, Kladovasilakis N, Gkagkari E, Petrakis S, et al.
J Funct Biomater
. 2023 Sep;
14(9).
PMID: 37754879
The latest developments in tissue engineering scaffolds have sparked a growing interest in the creation of controlled 3D cellular structures that emulate the intricate biophysical and biochemical elements found within...
7.
Harwood A, Petrakis S, Oktay Y, Pasterkamp R
Front Cell Dev Biol
. 2023 Aug;
11:1244425.
PMID: 37560163
No abstract available.
8.
Notopoulou S, Gkekas I, Petrakis S
Adv Exp Med Biol
. 2023 Jul;
1423:149-160.
PMID: 37525039
Parkinson's disease (PD) is the second most common neurodegenerative disorder, affecting millions of people worldwide. Despite considerable efforts, the underlying pathological mechanisms remain elusive, and yet, no treatment has been...
9.
Buijsen R, Hu M, Saez-Gonzalez M, Notopoulou S, Mina E, Koning W, et al.
Mov Disord
. 2023 Jun;
38(8):1428-1442.
PMID: 37278528
Background: Spinocerebellar ataxia type 1 (SCA1) is a neurodegenerative disease caused by a polyglutamine expansion in the ataxin-1 protein resulting in neuropathology including mutant ataxin-1 protein aggregation, aberrant neurodevelopment, and...
10.
Rasko T, Pande A, Radscheit K, Zink A, Singh M, Sommer C, et al.
Mol Biol Evol
. 2022 Oct;
39(10).
PMID: 36205081
Although new genes can arrive from modes other than duplication, few examples are well characterized. Given high expression in some human brain subregions and a putative link to psychological disorders...