Tamas Rasko
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Explore the profile of Tamas Rasko including associated specialties, affiliations and a list of published articles.
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25
Citations
588
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Recent Articles
1.
Gehrke L, Goncalves V, Andrae D, Rasko T, Ho P, Einsele H, et al.
Int J Mol Sci
. 2025 Jan;
25(24.
PMID: 39769449
The successful application of CAR-T cells in the treatment of hematologic malignancies has fundamentally changed cancer therapy. With increasing numbers of registered CAR-T cell clinical trials, efforts are being made...
2.
Devaraj A, Singh M, Narayanavari S, Yong G, Chen J, Wang J, et al.
Int J Mol Sci
. 2023 Apr;
24(8).
PMID: 37108449
Transposons are parasitic genetic elements that frequently hijack vital cellular processes of their host. HMGXB4 is a known Wnt signaling-regulating HMG-box protein, previously identified as a host-encoded factor of (SB)...
3.
Rasko T, Pande A, Radscheit K, Zink A, Singh M, Sommer C, et al.
Mol Biol Evol
. 2022 Oct;
39(10).
PMID: 36205081
Although new genes can arrive from modes other than duplication, few examples are well characterized. Given high expression in some human brain subregions and a putative link to psychological disorders...
4.
Li C, Wang H, Gil S, Germond A, Fountain C, Baldessari A, et al.
Mol Ther Methods Clin Dev
. 2022 Jun;
25:533.
PMID: 35662812
[This corrects the article DOI: 10.1016/j.omtm.2021.12.003.].
5.
Kolacsek O, Wachtl G, Fothi A, Schamberger A, Sandor S, Pergel E, et al.
Gene
. 2022 May;
834:146609.
PMID: 35609796
Transposable elements are widespread in all living organisms. In addition to self-reproduction, they are a major source of genetic variation that drives genome evolution but our knowledge of the functions...
6.
Li C, Wang H, Gil S, Germond A, Fountain C, Baldessari A, et al.
Mol Ther Methods Clin Dev
. 2022 Jan;
24:127-141.
PMID: 35036470
We tested a new hematopoietic stem cell (HSC) transduction/selection approach in rhesus macaques using HSC-tropic, integrating, helper-dependent adenovirus vectors (HDAd5/35++) designed for the expression of human γ-globin in red blood...
7.
Klockmeier K, Silva Ramos E, Rasko T, Pastor A, Wanker E
J Mol Biol
. 2021 Aug;
433(19):167184.
PMID: 34364876
Previously evidence was presented that the single-nucleotide polymorphism rs1344706 located in an intronic region of the ZNF804A gene is associated with reduced transcript levels in fetal brains. This genetic variation...
8.
Li C, Goncalves K, Rasko T, Pande A, Gil S, Liu Z, et al.
Blood Adv
. 2021 Mar;
5(5):1239-1249.
PMID: 33646305
We have developed an in vivo hemopoietic stem cell (HSC) gene therapy approach without the need for myelosuppressive conditioning and autologous HSC transplantation. It involves HSC mobilization and IV injection...
9.
Rotiroti M, Buracchi C, Arcangeli S, Galimberti S, Valsecchi M, Perriello V, et al.
Mol Ther
. 2020 Jun;
28(9):1974-1986.
PMID: 32526203
The successful implementation of chimeric antigen receptor (CAR)-T cell therapy in the clinical context of B cell malignancies has paved the way for further development in the more critical setting...
10.
Laidou S, Alanis-Lobato G, Pribyl J, Rasko T, Tichy B, Mikulasek K, et al.
Redox Biol
. 2020 Mar;
32:101458.
PMID: 32145456
Spinocerebellar ataxia type-1 (SCA1) is caused by an abnormally expanded polyglutamine (polyQ) tract in ataxin-1. These expansions are responsible for protein misfolding and self-assembly into intranuclear inclusion bodies (IIBs) that...