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Spiridione Garbisa

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Articles 43
Citations 788
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Recent Articles
1.
Sassi N, Biasutto L, Mattarei A, Carraro M, Giorgio V, Citta A, et al.
Biochim Biophys Acta . 2012 Mar; 1817(7):1095-106. PMID: 22433608
The mitochondriotropic compound 7-O-(4-triphenylphosphoniumbutyl)quercetin iodide (Q-7BTPI) in the μM concentration range caused necrotic death of cultured cells by acting as a prooxidant, with generation of superoxide anion in the mitochondria....
2.
Levis A, Minicucci N, Ricci P, Gennaro V, Garbisa S
Epidemiol Prev . 2011 Sep; 35(3-4):188-99. PMID: 21914915
The uncertainty about the relationship between the use of mobile phones (MPs: analogue and digital cellulars, and cordless) and the increase of head tumour risk can be solved by a...
3.
Aresu L, Giantin M, Morello E, Vascellari M, Castagnaro M, Lopparelli R, et al.
BMC Vet Res . 2011 Jul; 7:33. PMID: 21726449
Background: Malignant canine mammary tumors represent 50% of all neoplasms in female dogs. Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) are thought to be involved in tumor progression,...
4.
Levis A, Minicuci N, Ricci P, Gennaro V, Garbisa S
Environ Health . 2011 Jun; 10:59. PMID: 21679472
Background: Whether or not there is a relationship between use of mobile phones (analogue and digital cellulars, and cordless) and head tumour risk (brain tumours, acoustic neuromas, and salivary gland...
5.
Tassone E, Maran C, Masola V, Bradaschia A, Garbisa S, Onisto M
Pharmacol Res . 2010 Oct; 63(1):37-43. PMID: 20883786
Vascular endothelial growth factor (VEGF) is a key player in neo-angiogenesis; it sustains the progression of solid neoplasias, brain tumours included. It has recently been demonstrated that the use of...
6.
Biasutto L, Marotta E, Garbisa S, Zoratti M, Paradisi C
Molecules . 2010 Sep; 15(9):6570-9. PMID: 20877244
Resveratrol (trans-3,4',5-trihydroxystilbene) and quercetin (3,3',4',5,7-pentahydroxyflavone) are two naturally occurring polyphenols with the potential to exert beneficial health effects. Since their low bioavailability is a major obstacle to biomedical applications, efforts...
7.
Mattarei A, Biasutto L, Rastrelli F, Garbisa S, Marotta E, Zoratti M, et al.
Molecules . 2010 Jul; 15(7):4722-36. PMID: 20657388
The regioselective synthesis of several quercetin (3,3',4',5,7-pentahydroxy flavone) tetraesters bearing a single free OH on 5-C was achieved in good yield by proper choice of reaction conditions using common esterification...
8.
Gurrieri C, Piazza F, Gnoato M, Montini B, Biasutto L, Gattazzo C, et al.
J Pharmacol Exp Ther . 2009 Dec; 332(3):785-94. PMID: 19959748
Glycogen synthase kinase (GSK)-3 modulates the production of inflammatory cytokines. Because bleomycin (BLM) causes lung injury, which is characterized by an inflammatory response followed by a fibrotic degeneration, we postulated...
9.
Biasutto L, Marotta E, Mattarei A, Beltramello S, Caliceti P, Salmaso S, et al.
Cell Physiol Biochem . 2009 Nov; 24(5-6):557-66. PMID: 19910696
Model prodrugs of resveratrol carrying protecting substituents at the hydroxyls have been synthesised and tested. Resveratrol triacetate and resveratrol-tri-mPEG(1900) were formed by linking methyl groups or poly(ethylene glycol) chains, respectively,...
10.
Biasutto L, Marotta E, Bradaschia A, Fallica M, Mattarei A, Garbisa S, et al.
Bioorg Med Chem Lett . 2009 Oct; 19(23):6721-4. PMID: 19846300
We report the development of a chemical modification method of general applicability to polyphenols, which increases solubility to influence absorption. Glucosyl groups were added to the resveratrol kernel via a...