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Spiridione Garbisa

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Articles 43
Citations 788
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Recent Articles
11.
Biasutto L, Sassi N, Mattarei A, Marotta E, Cattelan P, Toninello A, et al.
Biochim Biophys Acta . 2009 Oct; 1797(2):189-96. PMID: 19835835
Mitochondria-targeted polyphenols are being developed with the intent to intervene on the levels of reactive oxygen species (ROS) in mitochondria. Polyphenols being more than just anti-oxidants, the interaction of these...
12.
De Marchi U, Biasutto L, Garbisa S, Toninello A, Zoratti M
Biochim Biophys Acta . 2009 Jun; 1787(12):1425-32. PMID: 19523917
The Ca(2+)- and oxidative stress-induced mitochondrial permeability transition (MPT) plays an important role in phenomena ranging from tissue damage upon infarction to muscle wasting in some forms of dystrophy. The...
13.
Biasutto L, Marotta E, De Marchi U, Beltramello S, Bradaschia A, Garbisa S, et al.
Cell Physiol Biochem . 2009 May; 23(4-6):425-30. PMID: 19471110
Caco-2 cells are widely used for transepithelial transport and metabolism studies. We analysed the metabolites produced from quercetin (Q) during transport of this flavonoid across Caco-2 monolayers and by plastic-adhering...
14.
Lorusso G, Vannini N, Sogno I, Generoso L, Garbisa S, Noonan D, et al.
Eur J Cancer . 2009 Feb; 45(8):1474-84. PMID: 19223175
Hyperforin, the major lipophilic compound contained in extracts of Hypericum perforatum, is responsible for the antidepressant activity associated with the extract. Recently, several other biological properties of Hyperforin have been...
15.
Mattarei A, Biasutto L, Marotta E, De Marchi U, Sassi N, Garbisa S, et al.
Chembiochem . 2008 Oct; 9(16):2633-42. PMID: 18837061
Mitochondria-targeted compounds are needed to act on a variety of processes that take place in these subcellular organelles and that have great pathophysiological relevance. In particular, redox-active molecules that are...
16.
Biasutto L, Mattarei A, Marotta E, Bradaschia A, Sassi N, Garbisa S, et al.
Bioorg Med Chem Lett . 2008 Oct; 18(20):5594-7. PMID: 18823777
To target natural polyphenols to the subcellular site where their redox properties might be exploited at best, that is, mitochondria, we have synthesised new proof-of-principle derivatives by linking resveratrol (3,4',5-trihydroxy-trans-stilbene)...
17.
Papparella I, Ceolotto G, Montemurro D, Antonello M, Garbisa S, Rossi G, et al.
J Nutr . 2008 Aug; 138(9):1596-601. PMID: 18716156
We previously documented a clear-cut antihypertensive effect of green teat extract (GTE), which was associated with correction of endothelial dysfunction and prevention of left ventricular hypertrophy in an angiotensin II...
18.
Yodkeeree S, Garbisa S, Limtrakul P
Acta Pharmacol Sin . 2008 Jun; 29(7):853-60. PMID: 18565284
Aim: Tetrahydrocurcumin (THC) is an active metabolite of curcumin. It has been reported to have similar pharmacological activity to curcumin. The proteases that participate in extracellular matrix (ECM) degradation are...
19.
Yodkeeree S, Chaiwangyen W, Garbisa S, Limtrakul P
J Nutr Biochem . 2008 May; 20(2):87-95. PMID: 18495463
Curcumin (Cur), a component of turmeric (Curcuma longa), has been reported to exhibit antimetastatic activities, but the mechanisms remain unclear. Other curcuminoids present in turmeric, demethoxycurcumin (DMC) and bisdemethoxycurcumin (BDMC)...
20.
Araldi E, DellAica I, Sogno I, Lorusso G, Garbisa S, Albini A
Curr Cancer Drug Targets . 2008 Mar; 8(2):146-55. PMID: 18336198
Prostate cancer is the most common cancer in men and one of the leading causes of cancer-related deaths in Western countries. The extraordinary biological heterogeneity, the increasing incidence of this...