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Sovan Sarkar

Explore the profile of Sovan Sarkar including associated specialties, affiliations and a list of published articles. Areas
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Articles 93
Citations 13802
Followers 0
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Recent Articles
1.
Aubry L, Barrett T, Sarkar S
Neural Regen Res . 2024 Nov; 20(9):2587-2588. PMID: 39503425
No abstract available.
2.
Kataura T, Sedlackova L, Sun C, Kocak G, Wilson N, Banks P, et al.
Cell Death Dis . 2024 May; 15(5):382. PMID: 38821960
Impairment of autophagy leads to an accumulation of misfolded proteins and damaged organelles and has been implicated in plethora of human diseases. Loss of autophagy in actively respiring cells has...
3.
Stanulovic V, Al Omair S, Reed M, Roberts J, Potluri S, Fulton-Ward T, et al.
Haematologica . 2024 May; 109(11):3505-3519. PMID: 38813748
T-cell acute lymphoblastic leukemia (T-ALL) is a cancer of the immune system. Approximately 20% of pediatric and 50% of adult T-ALL patients have refractory disease or relapse and die from...
4.
Binet R, Lambert J, Tomkova M, Tischfield S, Baggiolini A, Picaud S, et al.
Genes Dev . 2024 Feb; 38(1-2):70-94. PMID: 38316520
Since genome instability can drive cancer initiation and progression, cells have evolved highly effective and ubiquitous DNA damage response (DDR) programs. However, some cells (for example, in skin) are normally...
5.
Verma S, Das M, Sharma R, Yadav V, Thakur S, Sharma P, et al.
bioRxiv . 2023 Dec; PMID: 38076943
Phagosome maturation arrest (PMA) imposed by ( ) is a classic tool that helps evade macrophage anti-bacterial responses. The exclusion of RAB7, a small GTPase, from -phagosomes underscores PMA. Here...
6.
Korsgen M, Sun C, Seranova E, Zatyka M, Astuti D, Kataura T, et al.
STAR Protoc . 2023 Aug; 4(3):102529. PMID: 37624702
Autophagy, a catabolic process governing cellular and energy homeostasis, is essential for cell survival and human health. Here, we present a protocol for generating autophagy-deficient (ATG5) human neurons from human...
7.
Zatyka M, Rosenstock T, Sun C, Palhegyi A, Hughes G, Lara-Reyna S, et al.
Stem Cell Reports . 2023 May; 18(5):1090-1106. PMID: 37163979
Mitochondrial dysfunction involving mitochondria-associated ER membrane (MAM) dysregulation is implicated in the pathogenesis of late-onset neurodegenerative diseases, but understanding is limited for rare early-onset conditions. Loss of the MAM-resident protein...
8.
Binet R, Lambert J, Tomkova M, Tischfield S, Baggiolini A, Picaud S, et al.
bioRxiv . 2023 May; PMID: 37131595
Since genome instability can drive cancer initiation and progression, cells have evolved highly effective and ubiquitous DNA Damage Response (DDR) programs. However, some cells, in skin for example, are normally...
9.
Sun C, Seranova E, Cohen M, Chipara M, Roberts J, Astuti D, et al.
Cell Rep . 2023 Apr; 42(5):112372. PMID: 37086404
Autophagy is a homeostatic process critical for cellular survival, and its malfunction is implicated in human diseases including neurodegeneration. Loss of autophagy contributes to cytotoxicity and tissue degeneration, but the...
10.
Wilson N, Kataura T, Korsgen M, Sun C, Sarkar S, Korolchuk V
Trends Cell Biol . 2023 Mar; 33(9):788-802. PMID: 36878731
Autophagy is an intracellular degradation pathway that recycles subcellular components to maintain metabolic homeostasis. NAD is an essential metabolite that participates in energy metabolism and serves as a substrate for...