Sophie Le Gonidec
Overview
Explore the profile of Sophie Le Gonidec including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
2049
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Recent Articles
1.
Helissen O, Kermorgant M, Dejean S, Mercadie A, Le Gonidec S, Zahreddine R, et al.
Life (Basel)
. 2023 Mar;
13(3).
PMID: 36983999
Whether in real or simulated microgravity, Humans or animals, the kinetics of cardiovascular adaptation and its regulation by the autonomic nervous system (ANS) remain controversial. In this study, we used...
2.
Paccoud R, Saint-Laurent C, Piccolo E, Tajan M, Dortignac A, Pereira O, et al.
Sci Transl Med
. 2021 Apr;
13(591).
PMID: 33910978
Insulin resistance is a key event in type 2 diabetes onset and a major comorbidity of obesity. It results from a combination of fat excess-triggered defects, including lipotoxicity and metaflammation,...
3.
Guerard A, Laurent V, Fromont G, Esteve D, Gilhodes J, Bonnelye E, et al.
Int J Mol Sci
. 2021 Mar;
22(4).
PMID: 33671469
Bone metastasis remains the most frequent and the deadliest complication of prostate cancer (PCa). Mechanisms leading to the homing of tumor cells to bone remain poorly characterized. Role of chemokines...
4.
Clement E, Lazar I, Attane C, Carrie L, Dauvillier S, Ducoux-Petit M, et al.
EMBO J
. 2020 Jan;
39(3):e102525.
PMID: 31919869
Extracellular vesicles are emerging key actors in adipocyte communication. Notably, small extracellular vesicles shed by adipocytes stimulate fatty acid oxidation and migration in melanoma cells and these effects are enhanced...
5.
Mercader J, Sabater A, Le Gonidec S, Decaunes P, Chaplin A, Gomez-Zorita S, et al.
J Pharmacol Exp Ther
. 2019 Jul;
371(2):555-566.
PMID: 31270215
Novel mechanisms and health benefits have been recently suggested for the antidepressant drug phenelzine (PHE), known as a nonselective monoamine oxidase inhibitor. They include an antilipogenic action that could have...
6.
Lehuede C, Li X, Dauvillier S, Vaysse C, Franchet C, Clement E, et al.
Breast Cancer Res
. 2019 Jan;
21(1):7.
PMID: 30654824
Introduction: Clinical studies suggest that obesity, in addition to promoting breast cancer aggressiveness, is associated with a decrease in chemotherapy efficacy, although the mechanisms involved remain elusive. As chemotherapy is...
7.
Laurent V, Toulet A, Attane C, Milhas D, Dauvillier S, Zaidi F, et al.
Mol Cancer Res
. 2019 Jan;
17(3):821-835.
PMID: 30606769
Prostate gland is surrounded by periprostatic adipose tissue (PPAT), which is increasingly believed to play a paracrine role in prostate cancer progression. Our previous work demonstrates that adipocytes promote homing...
8.
Vinel C, Lukjanenko L, Batut A, Deleruyelle S, Pradere J, Le Gonidec S, et al.
Nat Med
. 2018 Aug;
24(9):1360-1371.
PMID: 30061698
Sarcopenia, the degenerative loss of skeletal muscle mass, quality and strength, lacks early diagnostic tools and new therapeutic strategies to prevent the frailty-to-disability transition often responsible for the medical institutionalization...
9.
Carpene C, Mercader J, Le Gonidec S, Schaak S, Mialet-Perez J, Zakaroff-Girard A, et al.
Br J Pharmacol
. 2018 Mar;
175(12):2428-2440.
PMID: 29582416
Background And Purpose: Phenelzine is an antidepressant drug known to increase the risk of hypertensive crisis when dietary tyramine is not restricted. However, this MAO inhibitor inhibits other enzymes not...
10.
Bertrand C, Pradere J, Geoffre N, Deleruyelle S, Masri B, Personnaz J, et al.
Endocrine
. 2018 Feb;
60(1):112-121.
PMID: 29392617
Purpose: Apelin treatment has been shown to improve insulin sensitivity in insulin resistant mice by acting in skeletal muscles. However, the effects of systemic apelin on the hepatic energy metabolism...