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Sophia B Chernikova

Explore the profile of Sophia B Chernikova including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 546
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Recent Articles
1.
Rodrigues A, Chernikova S, Wang Y, Trinh T, Solow-Cordero D, Alexandrova L, et al.
J Neurooncol . 2024 Apr; 168(1):125-138. PMID: 38563850
Purpose: Triple-negative breast cancer (TNBC) often metastasizes to the central nervous system (CNS) and has the highest propensity among breast cancer subtypes to develop leptomeningeal disease (LMD). LMD is a...
2.
Rodrigues A, Chernikova S, Wang Y, Trinh T, Solow-Cordero D, Alexandrova L, et al.
Res Sq . 2024 Feb; PMID: 38405839
Purpose: Triple-negative breast cancer (TNBC) is an aggressive subtype that often metastasizes to the brain. Leptomeningeal disease (LMD), a devastating brain metastasis common in TNBC, has limited treatment options. We...
3.
Thomas R, Nagpal S, Iv M, Soltys S, Bertrand S, Pelpola J, et al.
Clin Cancer Res . 2023 Jan; 29(2):502. PMID: 36647675
No abstract available.
4.
Deng J, Chernikova S, Wang Y, Rodriguez M, Andersen S, Umeh-Garcia M, et al.
Mol Cancer Ther . 2021 Oct; 20(11):2110-2116. PMID: 34635566
Development of metastases to central nervous system (CNS) is an increasing clinical issue following the diagnosis of advanced breast cancer. The propensity to metastasize to CNS varies by breast cancer...
5.
Chernikova S, Game J, Brown J
Oncotarget . 2019 May; 10(24):2336-2337. PMID: 31040924
No abstract available.
6.
Chernikova S, Nguyen R, Truong J, Mello S, Stafford J, Hay M, et al.
J Clin Invest . 2018 Oct; 128(12):5307-5321. PMID: 30371505
After the initial responsiveness of triple-negative breast cancers (TNBCs) to chemotherapy, they often recur as chemotherapy-resistant tumors, and this has been associated with upregulated homology-directed repair (HDR). Thus, inhibitors of...
7.
Deng L, Stafford J, Liu S, Chernikova S, Merchant M, Recht L, et al.
Neoplasia . 2016 Dec; 19(1):1-7. PMID: 27940247
Despite the approval of antiangiogenic therapy for glioblastoma multiforme (GBM) patients, survival benefits are still limited. One of the resistance mechanisms for antiangiogenic therapy is the induction of hypoxia and...
8.
Stafford J, Hirai T, Deng L, Chernikova S, Urata K, West B, et al.
Neuro Oncol . 2015 Nov; 18(6):797-806. PMID: 26538619
Background: Glioblastoma (GBM) may initially respond to treatment with ionizing radiation (IR), but the prognosis remains extremely poor because the tumors invariably recur. Using animal models, we previously showed that...
9.
Liu S, Alomran R, Chernikova S, Lartey F, Stafford J, Jang T, et al.
Neuro Oncol . 2013 Dec; 16(1):21-8. PMID: 24335554
Background: Tumor irradiation blocks local angiogenesis, forcing any recurrent tumor to form new vessels from circulating cells. We have previously demonstrated that the post-irradiation recurrence of human glioblastomas in the...
10.
Chernikova S, Brown J
Cell Cycle . 2012 Jul; 11(16):2980-4. PMID: 22825248
We have proposed that maintenance of genomic stability may constitute the basis for the tumor-suppressing activity of the Bre1 (RNF20/RNF40) complex. Revisiting the evidence we presented in our recent publication,...