Sonal S Sheth
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Explore the profile of Sonal S Sheth including associated specialties, affiliations and a list of published articles.
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8
Citations
380
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Recent Articles
1.
Friedman R, Van Laer L, Huentelman M, Sheth S, Eyken E, Corneveaux J, et al.
Hum Mol Genet
. 2008 Dec;
18(4):785-96.
PMID: 19047183
Age-related hearing impairment (ARHI), or presbycusis, is the most prevalent sensory impairment in the elderly. ARHI is a complex disease caused by an interaction between environmental and genetic factors. Here...
2.
Niu H, Makmura L, Shen T, Sheth S, Blair K, Friedman R
Genomics
. 2006 Feb;
88(3):302-8.
PMID: 16488112
The Eya1(bor) mutant hypomorph contains an intracisternal A particle insertion in intron 7 of the Eya1 gene that results in a 50% reduction in wild-type mRNA levels. The homozygous mutants...
3.
Ghazalpour A, Doss S, Sheth S, Ingram-Drake L, Schadt E, Lusis A, et al.
Genome Biol
. 2005 Jul;
6(7):R59.
PMID: 15998448
Background: A segregating population of (C57BL/6J x DBA/2J)F2 intercross mice was studied for obesity-related traits and for global gene expression in liver. Quantitative trait locus analyses were applied to the...
4.
Sheth S, Castellani L, Chari S, Wagg C, Thipphavong C, Bodnar J, et al.
J Lipid Res
. 2004 Nov;
46(1):123-34.
PMID: 15520447
Through a positional cloning approach, the thioredoxin-interacting protein gene (Txnip) was recently identified as causal for a form of combined hyperlipidemia in mice (Bodnar, J. S., A. Chatterjee, L. W....
5.
Donnelly K, Margosian M, Sheth S, Lusis A, Parks E
J Nutr
. 2004 Jun;
134(6):1475-80.
PMID: 15173414
The effect of decreased fatty acid oxidation on liver lipid metabolism in HcB-19 mice, a mouse model of hyperlipidemia (Txnip(-/-)), was investigated using metabolic labeling. De novo cholesterol synthesis and...
6.
Hui T, Sheth S, Diffley J, Potter D, Lusis A, Attie A, et al.
J Biol Chem
. 2004 Mar;
279(23):24387-93.
PMID: 15047687
Thioredoxin-interacting protein (Txnip) is a ubiquitous protein that binds with high affinity to thioredoxin and inhibits its ability to reduce sulfhydryl groups via NADPH oxidation. HcB-19 mice contain a nonsense...
7.
Sheth S, Deluna A, Allayee H, Lusis A
Curr Opin Lipidol
. 2002 Mar;
13(2):181-9.
PMID: 11891421
During the past year studies with mouse models have significantly clarified our understanding of atherosclerosis. Noteworthy achievements include: the discovery of a number of novel genes and pathways; new evidence...
8.
Bodnar J, Chatterjee A, Castellani L, Ross D, Ohmen J, Cavalcoli J, et al.
Nat Genet
. 2001 Dec;
30(1):110-6.
PMID: 11753387
Familial combined hyperlipidemia (FCHL, MIM-144250) is a common, multifactorial and heterogeneous dyslipidemia predisposing to premature coronary artery disease and characterized by elevated plasma triglycerides, cholesterol, or both. We identified a...