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Somnath Mazumder

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Articles 24
Citations 657
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Recent Articles
1.
Saha D, Pramanik A, Freville A, Siddiqui A, Pal U, Banerjee C, et al.
FEBS J . 2024 Jul; 291(19):4349-4371. PMID: 39003571
Non-canonical nucleotides, generated as oxidative metabolic by-products, significantly threaten the genome integrity of Plasmodium falciparum and thereby, their survival, owing to their mutagenic effects. PfHAM1, an evolutionarily conserved inosine/xanthosine triphosphate...
2.
Mazumder S, Bindu S, Debsharma S, Bandyopadhyay U
Biochem Pharmacol . 2024 May; 228:116283. PMID: 38750902
Non-steroidal anti-inflammatory drugs (NSAIDs) are most extensively used over-the-counter FDA-approved analgesic medicines for treating inflammation, musculoskeletal pain, arthritis, pyrexia and menstrual cramps. Moreover, aspirin is widely used against cardiovascular complications....
3.
Nag S, Banerjee C, Goyal M, Siddiqui A, Saha D, Mazumder S, et al.
iScience . 2024 Apr; 27(4):109467. PMID: 38558939
Alba domain proteins, owing to their functional plasticity, play a significant role in organisms. Here, we report an intrinsic DNase activity of PfAlba6 from , an etiological agent responsible for...
4.
Debsharma S, Pramanik S, Bindu S, Mazumder S, Das T, Pal U, et al.
iScience . 2024 Mar; 27(4):109384. PMID: 38550981
Gastric cancer (GC) is a deadly malignancy that demands effective therapeutic intervention capitalizing unique drug target/s. Here, we report that indomethacin, a cyclooxygenase non-selective non-steroidal anti-inflammatory drug, arrests GC cell...
5.
Kurkalang S, Roy S, Acharya A, Mazumder P, Mazumder S, Patra S, et al.
Cancer Sci . 2023 Oct; 114(12):4732-4746. PMID: 37792582
Oral squamous cell carcinoma of the gingivo-buccal region (OSCC-GB) is the most common cancer among men in India, and is associated with poor prognosis and frequent recurrence. Cellular heterogeneity in...
6.
Banerjee C, Nag S, Goyal M, Saha D, Siddiqui A, Mazumder S, et al.
Cell Rep . 2023 Mar; 42(4):112292. PMID: 36947546
Plasmodium falciparum Alba domain-containing protein Alba3 (PfAlba3) is ubiquitously expressed in intra-erythrocytic stages of Plasmodium falciparum, but the function of this protein is not yet established. Here, we report an...
7.
Debsharma S, Pramanik S, Bindu S, Mazumder S, Das T, Saha D, et al.
Br J Pharmacol . 2023 Mar; 180(18):2317-2340. PMID: 36914615
Background And Purpose: Mitochondrial oxidative stress, inflammation and apoptosis primarily underlie gastric mucosal injury caused by the widely used non-steroidal anti-inflammatory drugs (NSAIDs). Alternative gastroprotective strategies are therefore needed. Sirtuin-3...
8.
Mazumder S, Bindu S, De R, Debsharma S, Pramanik S, Bandyopadhyay U
Life Sci . 2022 Jul; 305:120753. PMID: 35787999
Gastroduodenal inflammation and ulcerative injuries are increasing due to expanding socio-economic stress, unhealthy food habits-lifestyle, smoking, alcoholism and usage of medicines like non-steroidal anti-inflammatory drugs. In fact, gastrointestinal (GI) complications,...
9.
De R, Mazumder S, Bandyopadhyay U
Cell Biol Toxicol . 2020 Oct; 37(3):333-366. PMID: 33067701
Mitochondria are double membrane-bound cellular work-horses constantly functioning to regulate vital aspects of cellular metabolism, bioenergetics, proliferation and death. Biogenesis, homeostasis and regulated turnover of mitochondria are stringently regulated to...
10.
Mazumder S, Barman M, Bandyopadhyay U, Bindu S
Life Sci . 2020 Aug; 258:118201. PMID: 32781070
Fibrotic lung diseases qualify among the most dreaded irreversible interstitial pulmonary complications with progressive yet largely unpredictable clinical course. Idiopathic pulmonary fibrosis (IPF) is the most challenging prototype characterized by...