Asim Azhar Siddiqui
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Explore the profile of Asim Azhar Siddiqui including associated specialties, affiliations and a list of published articles.
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16
Citations
135
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Recent Articles
1.
Saha D, Pramanik A, Freville A, Siddiqui A, Pal U, Banerjee C, et al.
FEBS J
. 2024 Jul;
291(19):4349-4371.
PMID: 39003571
Non-canonical nucleotides, generated as oxidative metabolic by-products, significantly threaten the genome integrity of Plasmodium falciparum and thereby, their survival, owing to their mutagenic effects. PfHAM1, an evolutionarily conserved inosine/xanthosine triphosphate...
2.
Nag S, Banerjee C, Goyal M, Siddiqui A, Saha D, Mazumder S, et al.
iScience
. 2024 Apr;
27(4):109467.
PMID: 38558939
Alba domain proteins, owing to their functional plasticity, play a significant role in organisms. Here, we report an intrinsic DNase activity of PfAlba6 from , an etiological agent responsible for...
3.
Siau J, Siddiqui A, Lau S, Kannan S, Peter S, Zeng Y, et al.
PLoS One
. 2024 Feb;
19(2):e0292479.
PMID: 38349923
Recombinase enzymes are extremely efficient at integrating very large DNA fragments into target genomes. However, intrinsic sequence specificities curtail their use to DNA sequences with sufficient homology to endogenous target...
4.
Siddiqui A, Peter S, Ngoh E, Wang C, Ng S, Dangerfield J, et al.
Front Bioeng Biotechnol
. 2023 Jul;
11:1198465.
PMID: 37425360
Reliable cell-based platforms to test and/or produce biologics in a sustainable manner are important for the biotech industry. Utilizing enhanced λ integrase, a sequence-specific DNA recombinase, we developed a novel...
5.
Banerjee C, Nag S, Goyal M, Saha D, Siddiqui A, Mazumder S, et al.
Cell Rep
. 2023 Mar;
42(4):112292.
PMID: 36947546
Plasmodium falciparum Alba domain-containing protein Alba3 (PfAlba3) is ubiquitously expressed in intra-erythrocytic stages of Plasmodium falciparum, but the function of this protein is not yet established. Here, we report an...
6.
Debsharma S, Pramanik S, Bindu S, Mazumder S, Das T, Saha D, et al.
Br J Pharmacol
. 2023 Mar;
180(18):2317-2340.
PMID: 36914615
Background And Purpose: Mitochondrial oxidative stress, inflammation and apoptosis primarily underlie gastric mucosal injury caused by the widely used non-steroidal anti-inflammatory drugs (NSAIDs). Alternative gastroprotective strategies are therefore needed. Sirtuin-3...
7.
Siddiqui A, Saha D, Iqbal M, Saha S, Sarkar S, Banerjee C, et al.
Biochim Biophys Acta Gen Subj
. 2020 Jun;
1864(10):129656.
PMID: 32512169
Background: Intracellular protein trafficking is crucial for survival of cell and proper functioning of the organelles; however, these pathways are not well studied in the malaria parasite. Its unique cellular...
8.
Mazumder S, De R, Debsharma S, Bindu S, Maity P, Sarkar S, et al.
J Biol Chem
. 2019 Apr;
294(20):8238-8258.
PMID: 30940726
The subcellular mechanism by which nonsteroidal anti-inflammatory drugs (NSAIDs) induce apoptosis in gastric cancer and normal mucosal cells is elusive because of the diverse cyclooxygenase-independent effects of these drugs. Using...
9.
Saha S, Siddiqui A, Pramanik S, Saha D, De R, Mazumder S, et al.
ACS Infect Dis
. 2018 Nov;
5(1):63-73.
PMID: 30472841
The rapid emergence of resistance against frontline antimalarial drugs essentially warrants the identification of new-generation antimalarials. Here, we describe the synthesis of ( E)-2-isopropyl-5-methyl-4-((2-(pyridin-4-yl)hydrazono)methyl)phenol (18), which binds ferriprotoporphyrin-IX (Fe-PPIX) (...
10.
De R, Sarkar S, Mazumder S, Debsharma S, Siddiqui A, Saha S, et al.
J Biol Chem
. 2018 Oct;
293(51):19740-19760.
PMID: 30366984
The indispensable role of macrophage migration inhibitory factor (MIF) in cancer cell proliferation is unambiguous, although which specific roles the cytokine plays to block apoptosis by preserving cell growth is...